Evaluation of the pediatric antimalarial prescriptions in a teaching hospital in Southeastern Nigeria

Background: Malaria in Nigeria with the highest morbidity and mortality in children between 6 months and 5 years continues to be a disease burden. In line with the World Health Organization recommendation of diagnosis in all ages before treatment, Nigeria provided guidelines on parasite-based diagno...

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Autor principal:	Adaobi Uchenna Mosanya
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	antimalarials artemisinin child humans incidence malaria nigeria outpatients parasites prescriptions Medicine R Nursing RT1-120
Acceso en línea:	https://doaj.org/article/8287e24ebc344e6c8fe4948bdc6bdbd8
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spelling	oai:doaj.org-article:8287e24ebc344e6c8fe4948bdc6bdbd82021-11-12T10:09:47ZEvaluation of the pediatric antimalarial prescriptions in a teaching hospital in Southeastern Nigeria2348-33342348-506X10.4103/cjhr.cjhr_98_19https://doaj.org/article/8287e24ebc344e6c8fe4948bdc6bdbd82021-01-01T00:00:00Zhttp://www.cjhr.org/article.asp?issn=2348-3334;year=2021;volume=8;issue=2;spage=79;epage=83;aulast=Mosanyahttps://doaj.org/toc/2348-3334https://doaj.org/toc/2348-506XBackground: Malaria in Nigeria with the highest morbidity and mortality in children between 6 months and 5 years continues to be a disease burden. In line with the World Health Organization recommendation of diagnosis in all ages before treatment, Nigeria provided guidelines on parasite-based diagnosis. Therefore, in order to achieve its preelimination and the reduction of mortality caused by it to zero by 2020, it is necessary to assess the compliance of the prescribers to the guidelines. Objectives: The objectives of this study were to determine the cases who were diagnosed based on positive malaria parasite test and the level of compliance of the prescribers to the National Malaria Treatment Guidelines. Methods: A total of 3034 prescriptions of antimalarial drugs were collected between 2003 and 2011 in the Outpatient Department of the Pediatric Clinic. Data were analyzed using Microsoft Excel and SPSS V.20.0 and grouped into two: prepolicy (2003–2005) and postpolicy (2006–2011) periods. Descriptive and inferential statistics were used at P < 0.05 level of significance. Results: The study revealed that diagnosis based on positive malaria parasite test was 4.8% of 2765 patients. There was a noticeable increase in the prescription of artemisinin combination therapy in the postpolicy period (32.6%), but the compliance to the Antimalarial Treatment Guideline was low (23.8%). Conclusion: There was a high incidence of empirical diagnoses of malaria and treatment. Many of the artemisinin-based combination therapies prescribed were not recommended.Adaobi Uchenna MosanyaWolters Kluwer Medknow Publicationsarticle antimalarialsartemisininchildhumansincidencemalarianigeriaoutpatientsparasitesprescriptions MedicineRNursingRT1-120ENCHRISMED Journal of Health and Research, Vol 8, Iss 2, Pp 79-83 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	antimalarials artemisinin child humans incidence malaria nigeria outpatients parasites prescriptions Medicine R Nursing RT1-120
spellingShingle	antimalarials artemisinin child humans incidence malaria nigeria outpatients parasites prescriptions Medicine R Nursing RT1-120 Adaobi Uchenna Mosanya Evaluation of the pediatric antimalarial prescriptions in a teaching hospital in Southeastern Nigeria
description	Background: Malaria in Nigeria with the highest morbidity and mortality in children between 6 months and 5 years continues to be a disease burden. In line with the World Health Organization recommendation of diagnosis in all ages before treatment, Nigeria provided guidelines on parasite-based diagnosis. Therefore, in order to achieve its preelimination and the reduction of mortality caused by it to zero by 2020, it is necessary to assess the compliance of the prescribers to the guidelines. Objectives: The objectives of this study were to determine the cases who were diagnosed based on positive malaria parasite test and the level of compliance of the prescribers to the National Malaria Treatment Guidelines. Methods: A total of 3034 prescriptions of antimalarial drugs were collected between 2003 and 2011 in the Outpatient Department of the Pediatric Clinic. Data were analyzed using Microsoft Excel and SPSS V.20.0 and grouped into two: prepolicy (2003–2005) and postpolicy (2006–2011) periods. Descriptive and inferential statistics were used at P < 0.05 level of significance. Results: The study revealed that diagnosis based on positive malaria parasite test was 4.8% of 2765 patients. There was a noticeable increase in the prescription of artemisinin combination therapy in the postpolicy period (32.6%), but the compliance to the Antimalarial Treatment Guideline was low (23.8%). Conclusion: There was a high incidence of empirical diagnoses of malaria and treatment. Many of the artemisinin-based combination therapies prescribed were not recommended.
format	article
author	Adaobi Uchenna Mosanya
author_facet	Adaobi Uchenna Mosanya
author_sort	Adaobi Uchenna Mosanya
title	Evaluation of the pediatric antimalarial prescriptions in a teaching hospital in Southeastern Nigeria
title_short	Evaluation of the pediatric antimalarial prescriptions in a teaching hospital in Southeastern Nigeria
title_full	Evaluation of the pediatric antimalarial prescriptions in a teaching hospital in Southeastern Nigeria
title_fullStr	Evaluation of the pediatric antimalarial prescriptions in a teaching hospital in Southeastern Nigeria
title_full_unstemmed	Evaluation of the pediatric antimalarial prescriptions in a teaching hospital in Southeastern Nigeria
title_sort	evaluation of the pediatric antimalarial prescriptions in a teaching hospital in southeastern nigeria
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/8287e24ebc344e6c8fe4948bdc6bdbd8
work_keys_str_mv	AT adaobiuchennamosanya evaluationofthepediatricantimalarialprescriptionsinateachinghospitalinsoutheasternnigeria
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Evaluation of the pediatric antimalarial prescriptions in a teaching hospital in Southeastern Nigeria

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