A comparative study of libido in drakes: from phenotypes to molecules

ABSTRACT: Low fertilization rate is the main reason to limit the development of artificial insemination (AI) technology in ducks. However, the libido of male livestock has been confirmed to be related to semen quality and fertilization rate, and we found that the libido of drakes was different. Thus...

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Autores principales:	Qingyuan Ouyang, Dewei Bao, Yao Lu, Jiwei Hu, Bo Hu, Cong Lan, Shenqiang Hu, Hua He, Hehe Liu, Liang Li, Jiwen Wang
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	drakes libido obesity transcriptome Animal culture SF1-1100
Acceso en línea:	https://doaj.org/article/8293ea9e6b30411a87b55ca5709ab73f
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spelling	oai:doaj.org-article:8293ea9e6b30411a87b55ca5709ab73f2021-11-24T04:22:43ZA comparative study of libido in drakes: from phenotypes to molecules0032-579110.1016/j.psj.2021.101503https://doaj.org/article/8293ea9e6b30411a87b55ca5709ab73f2021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S0032579121005253https://doaj.org/toc/0032-5791ABSTRACT: Low fertilization rate is the main reason to limit the development of artificial insemination (AI) technology in ducks. However, the libido of male livestock has been confirmed to be related to semen quality and fertilization rate, and we found that the libido of drakes was different. Thus, the research on the libido of drakes may be the key to further develop and apply AI technology. In this research, we established the first scoring standard for libido evaluation in drakes based on the performance of drakes during training period. Phenotypically, the body weight of high libido group was lighter than that of the other groups, while the weight of testis and epididymis in the high libido group was higher than that in the low libido group. Furthermore, we constructed the first expression profile of hypothalamus, pituitary, testis, and epididymis of drakes with high or low libido. There were 2, 1822, 214, and 892 differentially expressed genes (DEGs) in hypothalamus, pituitary, testis, and epididymis. The expression and sequence of Translocation Associated Membrane Protein 2 (TRAM2) were different in high and low libido drakes, indicating that it may be a candidate gene related to drake's libido. The estrogen, prolactin, and oxytocin signaling pathways were all activated in the pituitary of the low libido group. Meanwhile, the metabolic and oxidative phosphorylation pathways were enriched by DEGs in pituitary, testis and epididymis. Our research reveals that the difference in metabolic may cause changes in body weight of drakes, resulting in altered hormone levels and oxidative phosphorylation of gonad, which negatively affects libido and spermatogenesis in drakes. These results provide novel insights into the avian libido and will help better understand the underlying molecular mechanisms.Qingyuan OuyangDewei BaoYao LuJiwei HuBo HuCong LanShenqiang HuHua HeHehe LiuLiang LiJiwen WangElsevierarticledrakeslibidoobesitytranscriptomeAnimal cultureSF1-1100ENPoultry Science, Vol 100, Iss 12, Pp 101503- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	drakes libido obesity transcriptome Animal culture SF1-1100
spellingShingle	drakes libido obesity transcriptome Animal culture SF1-1100 Qingyuan Ouyang Dewei Bao Yao Lu Jiwei Hu Bo Hu Cong Lan Shenqiang Hu Hua He Hehe Liu Liang Li Jiwen Wang A comparative study of libido in drakes: from phenotypes to molecules
description	ABSTRACT: Low fertilization rate is the main reason to limit the development of artificial insemination (AI) technology in ducks. However, the libido of male livestock has been confirmed to be related to semen quality and fertilization rate, and we found that the libido of drakes was different. Thus, the research on the libido of drakes may be the key to further develop and apply AI technology. In this research, we established the first scoring standard for libido evaluation in drakes based on the performance of drakes during training period. Phenotypically, the body weight of high libido group was lighter than that of the other groups, while the weight of testis and epididymis in the high libido group was higher than that in the low libido group. Furthermore, we constructed the first expression profile of hypothalamus, pituitary, testis, and epididymis of drakes with high or low libido. There were 2, 1822, 214, and 892 differentially expressed genes (DEGs) in hypothalamus, pituitary, testis, and epididymis. The expression and sequence of Translocation Associated Membrane Protein 2 (TRAM2) were different in high and low libido drakes, indicating that it may be a candidate gene related to drake's libido. The estrogen, prolactin, and oxytocin signaling pathways were all activated in the pituitary of the low libido group. Meanwhile, the metabolic and oxidative phosphorylation pathways were enriched by DEGs in pituitary, testis and epididymis. Our research reveals that the difference in metabolic may cause changes in body weight of drakes, resulting in altered hormone levels and oxidative phosphorylation of gonad, which negatively affects libido and spermatogenesis in drakes. These results provide novel insights into the avian libido and will help better understand the underlying molecular mechanisms.
format	article
author	Qingyuan Ouyang Dewei Bao Yao Lu Jiwei Hu Bo Hu Cong Lan Shenqiang Hu Hua He Hehe Liu Liang Li Jiwen Wang
author_facet	Qingyuan Ouyang Dewei Bao Yao Lu Jiwei Hu Bo Hu Cong Lan Shenqiang Hu Hua He Hehe Liu Liang Li Jiwen Wang
author_sort	Qingyuan Ouyang
title	A comparative study of libido in drakes: from phenotypes to molecules
title_short	A comparative study of libido in drakes: from phenotypes to molecules
title_full	A comparative study of libido in drakes: from phenotypes to molecules
title_fullStr	A comparative study of libido in drakes: from phenotypes to molecules
title_full_unstemmed	A comparative study of libido in drakes: from phenotypes to molecules
title_sort	comparative study of libido in drakes: from phenotypes to molecules
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/8293ea9e6b30411a87b55ca5709ab73f
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A comparative study of libido in drakes: from phenotypes to molecules

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