The myosin X motor is optimized for movement on actin bundles
Myosin X is a molecular motor unique in its ability to generate filopodia, but the mechanism explaining this behaviour is not known. Here, through a combination of structure, single-molecule assays and modelling the authors show that myosin X is optimized for transport along actin bundles.
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Nature Portfolio
2016
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oai:doaj.org-article:82998216bea24bff892439a8a874030a2021-12-02T14:39:54ZThe myosin X motor is optimized for movement on actin bundles10.1038/ncomms124562041-1723https://doaj.org/article/82998216bea24bff892439a8a874030a2016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12456https://doaj.org/toc/2041-1723Myosin X is a molecular motor unique in its ability to generate filopodia, but the mechanism explaining this behaviour is not known. Here, through a combination of structure, single-molecule assays and modelling the authors show that myosin X is optimized for transport along actin bundles.Virginie RoparsZhaohui YangTatiana IsabetFlorian BlancKaifeng ZhouTianming LinXiaoyan LiuPascale HissierFrédéric SamazanBéatrice AmiguesEric D. YangHyokeun ParkOlena PylypenkoMarco CecchiniCharles V. SindelarH. Lee SweeneyAnne HoudusseNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
| institution |
DOAJ |
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DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Virginie Ropars Zhaohui Yang Tatiana Isabet Florian Blanc Kaifeng Zhou Tianming Lin Xiaoyan Liu Pascale Hissier Frédéric Samazan Béatrice Amigues Eric D. Yang Hyokeun Park Olena Pylypenko Marco Cecchini Charles V. Sindelar H. Lee Sweeney Anne Houdusse The myosin X motor is optimized for movement on actin bundles |
| description |
Myosin X is a molecular motor unique in its ability to generate filopodia, but the mechanism explaining this behaviour is not known. Here, through a combination of structure, single-molecule assays and modelling the authors show that myosin X is optimized for transport along actin bundles. |
| format |
article |
| author |
Virginie Ropars Zhaohui Yang Tatiana Isabet Florian Blanc Kaifeng Zhou Tianming Lin Xiaoyan Liu Pascale Hissier Frédéric Samazan Béatrice Amigues Eric D. Yang Hyokeun Park Olena Pylypenko Marco Cecchini Charles V. Sindelar H. Lee Sweeney Anne Houdusse |
| author_facet |
Virginie Ropars Zhaohui Yang Tatiana Isabet Florian Blanc Kaifeng Zhou Tianming Lin Xiaoyan Liu Pascale Hissier Frédéric Samazan Béatrice Amigues Eric D. Yang Hyokeun Park Olena Pylypenko Marco Cecchini Charles V. Sindelar H. Lee Sweeney Anne Houdusse |
| author_sort |
Virginie Ropars |
| title |
The myosin X motor is optimized for movement on actin bundles |
| title_short |
The myosin X motor is optimized for movement on actin bundles |
| title_full |
The myosin X motor is optimized for movement on actin bundles |
| title_fullStr |
The myosin X motor is optimized for movement on actin bundles |
| title_full_unstemmed |
The myosin X motor is optimized for movement on actin bundles |
| title_sort |
myosin x motor is optimized for movement on actin bundles |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/82998216bea24bff892439a8a874030a |
| work_keys_str_mv |
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