The epidemiology of fracture-related infections in Germany

Abstract The epidemiology of fracture-related infection (FRI) is unknown, which makes it difficult to estimate future demands and evaluate progress in infection prevention. Therefore, we aimed to determine the nationwide burden’s development over the last decade as a function of age group and gender...

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Autores principales: Nike Walter, Markus Rupp, Siegmund Lang, Volker Alt
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/82a8fc0786a4479bb181c979c27692e5
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spelling oai:doaj.org-article:82a8fc0786a4479bb181c979c27692e52021-12-02T14:59:09ZThe epidemiology of fracture-related infections in Germany10.1038/s41598-021-90008-w2045-2322https://doaj.org/article/82a8fc0786a4479bb181c979c27692e52021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-90008-whttps://doaj.org/toc/2045-2322Abstract The epidemiology of fracture-related infection (FRI) is unknown, which makes it difficult to estimate future demands and evaluate progress in infection prevention. Therefore, we aimed to determine the nationwide burden’s development over the last decade as a function of age group and gender. FRI prevalence as a function of age group and gender was quantified based on annual ICD-10 diagnosis codes from German medical institutions between 2008 through 2018, provided by the Federal Statistical Office of Germany (Destatis). The prevalence of FRI increased by 0.28 from 8.4 cases per 100,000 inhabitants to 10.7 cases per 100,000 inhabitants between 2008 and 2018. The proportion of fractures resulting in FRI increased from 1.05 to 1.23%. Gender distribution was equal. Patients aged 60–69 years and 70–79 years comprised the largest internal proportion with 20.2% and 20.7%, respectively, whereby prevalence increased with age group. A trend towards more diagnoses in older patients was observed with a growth rate of 0.63 for patients older than 90 years. Increasing rates of fracture-related infection especially in older patients indicate an upcoming challenge for stakeholders in health care systems. Newly emerging treatment strategies, prevention methods and interdisciplinary approaches are strongly required.Nike WalterMarkus RuppSiegmund LangVolker AltNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Nike Walter
Markus Rupp
Siegmund Lang
Volker Alt
The epidemiology of fracture-related infections in Germany
description Abstract The epidemiology of fracture-related infection (FRI) is unknown, which makes it difficult to estimate future demands and evaluate progress in infection prevention. Therefore, we aimed to determine the nationwide burden’s development over the last decade as a function of age group and gender. FRI prevalence as a function of age group and gender was quantified based on annual ICD-10 diagnosis codes from German medical institutions between 2008 through 2018, provided by the Federal Statistical Office of Germany (Destatis). The prevalence of FRI increased by 0.28 from 8.4 cases per 100,000 inhabitants to 10.7 cases per 100,000 inhabitants between 2008 and 2018. The proportion of fractures resulting in FRI increased from 1.05 to 1.23%. Gender distribution was equal. Patients aged 60–69 years and 70–79 years comprised the largest internal proportion with 20.2% and 20.7%, respectively, whereby prevalence increased with age group. A trend towards more diagnoses in older patients was observed with a growth rate of 0.63 for patients older than 90 years. Increasing rates of fracture-related infection especially in older patients indicate an upcoming challenge for stakeholders in health care systems. Newly emerging treatment strategies, prevention methods and interdisciplinary approaches are strongly required.
format article
author Nike Walter
Markus Rupp
Siegmund Lang
Volker Alt
author_facet Nike Walter
Markus Rupp
Siegmund Lang
Volker Alt
author_sort Nike Walter
title The epidemiology of fracture-related infections in Germany
title_short The epidemiology of fracture-related infections in Germany
title_full The epidemiology of fracture-related infections in Germany
title_fullStr The epidemiology of fracture-related infections in Germany
title_full_unstemmed The epidemiology of fracture-related infections in Germany
title_sort epidemiology of fracture-related infections in germany
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/82a8fc0786a4479bb181c979c27692e5
work_keys_str_mv AT nikewalter theepidemiologyoffracturerelatedinfectionsingermany
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AT siegmundlang epidemiologyoffracturerelatedinfectionsingermany
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