Toe-brachial index is beyond a peripheral issue in patients with type 2 diabetes.

<h4>Background</h4>Atherosclerosis is the leading cause of death in patients with diabetes. We aimed to evaluate the association between ankle-brachial index (ABI) and toe-brachial index (TBI) with carotid intima-media thickness (CIMT) in patients with type 2 diabetes (T2DM).<h4>Me...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Gisoo Darban Hosseini Amirkhiz, Mohammad Reza Babaei, Nahid Hashemi Madani, Mohammad Ebrahim Khamseh
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/82aa6028e1a042bf934a2e51ad5c823f
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:82aa6028e1a042bf934a2e51ad5c823f
record_format dspace
spelling oai:doaj.org-article:82aa6028e1a042bf934a2e51ad5c823f2021-12-02T20:10:39ZToe-brachial index is beyond a peripheral issue in patients with type 2 diabetes.1932-620310.1371/journal.pone.0253138https://doaj.org/article/82aa6028e1a042bf934a2e51ad5c823f2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0253138https://doaj.org/toc/1932-6203<h4>Background</h4>Atherosclerosis is the leading cause of death in patients with diabetes. We aimed to evaluate the association between ankle-brachial index (ABI) and toe-brachial index (TBI) with carotid intima-media thickness (CIMT) in patients with type 2 diabetes (T2DM).<h4>Methods</h4>This cross sectional study included 296 patients with T2DM who met the American Diabetes Association criteria for the assessment of peripheral arterial atherosclerosis. The ABI ≤ 0.9 and TBI ≤ 0.7 were considered as abnormal values. Linear and logistic regression analyses were performed to evaluate the association between TBI/ABI and CIMT.<h4>Results</h4>Right CIMT was significantly greater in the low TBI group (p = 0.03) while, left CIMT did not show a significant difference. Each 0.1-unit decrease in TBI value was independently associated with 0.017 mm increase in the right CIMT (β ± SE; -0.017 ± 0.005, p = 0.002) and with odds of the presence of increased CIMT [odds ratio and 95% confidence interval: 1.21 (1.02, 1.44)] after adjustment with all traditional risk factors. There was not any significant association between ABI and increased CIMT.<h4>Conclusions</h4>Beyond a suitable tool for the diagnosis of peripheral artery disease in patients with T2DM, TBI can be applied for prediction of subclinical carotid atherosclerosis.Gisoo Darban Hosseini AmirkhizMohammad Reza BabaeiNahid Hashemi MadaniMohammad Ebrahim KhamsehPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0253138 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Gisoo Darban Hosseini Amirkhiz
Mohammad Reza Babaei
Nahid Hashemi Madani
Mohammad Ebrahim Khamseh
Toe-brachial index is beyond a peripheral issue in patients with type 2 diabetes.
description <h4>Background</h4>Atherosclerosis is the leading cause of death in patients with diabetes. We aimed to evaluate the association between ankle-brachial index (ABI) and toe-brachial index (TBI) with carotid intima-media thickness (CIMT) in patients with type 2 diabetes (T2DM).<h4>Methods</h4>This cross sectional study included 296 patients with T2DM who met the American Diabetes Association criteria for the assessment of peripheral arterial atherosclerosis. The ABI ≤ 0.9 and TBI ≤ 0.7 were considered as abnormal values. Linear and logistic regression analyses were performed to evaluate the association between TBI/ABI and CIMT.<h4>Results</h4>Right CIMT was significantly greater in the low TBI group (p = 0.03) while, left CIMT did not show a significant difference. Each 0.1-unit decrease in TBI value was independently associated with 0.017 mm increase in the right CIMT (β ± SE; -0.017 ± 0.005, p = 0.002) and with odds of the presence of increased CIMT [odds ratio and 95% confidence interval: 1.21 (1.02, 1.44)] after adjustment with all traditional risk factors. There was not any significant association between ABI and increased CIMT.<h4>Conclusions</h4>Beyond a suitable tool for the diagnosis of peripheral artery disease in patients with T2DM, TBI can be applied for prediction of subclinical carotid atherosclerosis.
format article
author Gisoo Darban Hosseini Amirkhiz
Mohammad Reza Babaei
Nahid Hashemi Madani
Mohammad Ebrahim Khamseh
author_facet Gisoo Darban Hosseini Amirkhiz
Mohammad Reza Babaei
Nahid Hashemi Madani
Mohammad Ebrahim Khamseh
author_sort Gisoo Darban Hosseini Amirkhiz
title Toe-brachial index is beyond a peripheral issue in patients with type 2 diabetes.
title_short Toe-brachial index is beyond a peripheral issue in patients with type 2 diabetes.
title_full Toe-brachial index is beyond a peripheral issue in patients with type 2 diabetes.
title_fullStr Toe-brachial index is beyond a peripheral issue in patients with type 2 diabetes.
title_full_unstemmed Toe-brachial index is beyond a peripheral issue in patients with type 2 diabetes.
title_sort toe-brachial index is beyond a peripheral issue in patients with type 2 diabetes.
publisher Public Library of Science (PLoS)
publishDate 2021
url https://doaj.org/article/82aa6028e1a042bf934a2e51ad5c823f
work_keys_str_mv AT gisoodarbanhosseiniamirkhiz toebrachialindexisbeyondaperipheralissueinpatientswithtype2diabetes
AT mohammadrezababaei toebrachialindexisbeyondaperipheralissueinpatientswithtype2diabetes
AT nahidhashemimadani toebrachialindexisbeyondaperipheralissueinpatientswithtype2diabetes
AT mohammadebrahimkhamseh toebrachialindexisbeyondaperipheralissueinpatientswithtype2diabetes
_version_ 1718374955986452480