Inferring a nonlinear biochemical network model from a heterogeneous single-cell time course data

Abstract Mathematical modeling and analysis of biochemical reaction networks are key routines in computational systems biology and biophysics; however, it remains difficult to choose the most valid model. Here, we propose a computational framework for data-driven and systematic inference of a nonlin...

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Autores principales: Yuki Shindo, Yohei Kondo, Yasushi Sako
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/82ad5b244fc04aa09dfb7172228676c1
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