WASH maintains NKp46+ ILC3 cells by promoting AHR expression

WASH maintains NKp46+ ILC3 cells by promoting AHR expression

Innate lymphoid cells (ILC) are thought to direct immune responses, but little is known about the development and maintenance of ILC subsets. Here the authors show that WASH maintains the pool of NKp46+ ILC3s by recruiting Arid1a to the aryl hydrocarbon receptor promoter and inducing its expression.

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Autores principales: Pengyan Xia, Jing Liu, Shuo Wang, Buqing Ye, Ying Du, Zhen Xiong, Ze-Guang Han, Liang Tong, Zusen Fan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/82ad5b38f43c48979a1f9a1fb0f01cd2
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spelling oai:doaj.org-article:82ad5b38f43c48979a1f9a1fb0f01cd22021-12-02T14:40:47ZWASH maintains NKp46+ ILC3 cells by promoting AHR expression10.1038/ncomms156852041-1723https://doaj.org/article/82ad5b38f43c48979a1f9a1fb0f01cd22017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15685https://doaj.org/toc/2041-1723Innate lymphoid cells (ILC) are thought to direct immune responses, but little is known about the development and maintenance of ILC subsets. Here the authors show that WASH maintains the pool of NKp46+ ILC3s by recruiting Arid1a to the aryl hydrocarbon receptor promoter and inducing its expression.Pengyan XiaJing LiuShuo WangBuqing YeYing DuZhen XiongZe-Guang HanLiang TongZusen FanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Pengyan Xia
Jing Liu
Shuo Wang
Buqing Ye
Ying Du
Zhen Xiong
Ze-Guang Han
Liang Tong
Zusen Fan
WASH maintains NKp46+ ILC3 cells by promoting AHR expression
description Innate lymphoid cells (ILC) are thought to direct immune responses, but little is known about the development and maintenance of ILC subsets. Here the authors show that WASH maintains the pool of NKp46+ ILC3s by recruiting Arid1a to the aryl hydrocarbon receptor promoter and inducing its expression.
format article
author Pengyan Xia
Jing Liu
Shuo Wang
Buqing Ye
Ying Du
Zhen Xiong
Ze-Guang Han
Liang Tong
Zusen Fan
author_facet Pengyan Xia
Jing Liu
Shuo Wang
Buqing Ye
Ying Du
Zhen Xiong
Ze-Guang Han
Liang Tong
Zusen Fan
author_sort Pengyan Xia
title WASH maintains NKp46+ ILC3 cells by promoting AHR expression
title_short WASH maintains NKp46+ ILC3 cells by promoting AHR expression
title_full WASH maintains NKp46+ ILC3 cells by promoting AHR expression
title_fullStr WASH maintains NKp46+ ILC3 cells by promoting AHR expression
title_full_unstemmed WASH maintains NKp46+ ILC3 cells by promoting AHR expression
title_sort wash maintains nkp46+ ilc3 cells by promoting ahr expression
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/82ad5b38f43c48979a1f9a1fb0f01cd2
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AT jingliu washmaintainsnkp46ilc3cellsbypromotingahrexpression
AT shuowang washmaintainsnkp46ilc3cellsbypromotingahrexpression
AT buqingye washmaintainsnkp46ilc3cellsbypromotingahrexpression
AT yingdu washmaintainsnkp46ilc3cellsbypromotingahrexpression
AT zhenxiong washmaintainsnkp46ilc3cellsbypromotingahrexpression
AT zeguanghan washmaintainsnkp46ilc3cellsbypromotingahrexpression
AT liangtong washmaintainsnkp46ilc3cellsbypromotingahrexpression
AT zusenfan washmaintainsnkp46ilc3cellsbypromotingahrexpression
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