Ectopic PDX-1 expression directly reprograms human keratinocytes along pancreatic insulin-producing cells fate.
<h4>Background</h4>Cellular differentiation and lineage commitment have previously been considered irreversible processes. However, recent studies have indicated that differentiated adult cells can be reprogrammed to pluripotency and, in some cases, directly into alternate committed line...
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Auteurs principaux: | Michal Mauda-Havakuk, Naomi Litichever, Ellad Chernichovski, Odelia Nakar, Eyal Winkler, Ram Mazkereth, Arie Orenstein, Eran Bar-Meir, Philippe Ravassard, Irit Meivar-Levy, Sarah Ferber |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/82adb1dce3cc4c6193a704913d26fed7 |
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