CSL controls telomere maintenance and genome stability in human dermal fibroblasts
Conversion of dermal fibroblasts into Cancer Associated Fibroblasts (CAFs) can play an important role in keratinocyte tumour development. Here the authors reveal that CSL plays a role in maintenance of telomeres and genomic integrity in both dermal fibroblasts and CAFs.
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Nature Portfolio
2019
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oai:doaj.org-article:82b5056962d14041aae036cba6d017e32021-12-02T16:58:25ZCSL controls telomere maintenance and genome stability in human dermal fibroblasts10.1038/s41467-019-11785-72041-1723https://doaj.org/article/82b5056962d14041aae036cba6d017e32019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11785-7https://doaj.org/toc/2041-1723Conversion of dermal fibroblasts into Cancer Associated Fibroblasts (CAFs) can play an important role in keratinocyte tumour development. Here the authors reveal that CSL plays a role in maintenance of telomeres and genomic integrity in both dermal fibroblasts and CAFs.Giulia BottoniAtul KatarkarBeatrice TassoneSoumitra GhoshAndrea ClocchiattiSandro GoruppiPino BordignonParis JafariFabio TordiniThomas LunardiWolfram HoetzeneckerVictor NeelJoachim LingnerG. Paolo DottoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019) |
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DOAJ |
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DOAJ |
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EN |
topic |
Science Q |
spellingShingle |
Science Q Giulia Bottoni Atul Katarkar Beatrice Tassone Soumitra Ghosh Andrea Clocchiatti Sandro Goruppi Pino Bordignon Paris Jafari Fabio Tordini Thomas Lunardi Wolfram Hoetzenecker Victor Neel Joachim Lingner G. Paolo Dotto CSL controls telomere maintenance and genome stability in human dermal fibroblasts |
description |
Conversion of dermal fibroblasts into Cancer Associated Fibroblasts (CAFs) can play an important role in keratinocyte tumour development. Here the authors reveal that CSL plays a role in maintenance of telomeres and genomic integrity in both dermal fibroblasts and CAFs. |
format |
article |
author |
Giulia Bottoni Atul Katarkar Beatrice Tassone Soumitra Ghosh Andrea Clocchiatti Sandro Goruppi Pino Bordignon Paris Jafari Fabio Tordini Thomas Lunardi Wolfram Hoetzenecker Victor Neel Joachim Lingner G. Paolo Dotto |
author_facet |
Giulia Bottoni Atul Katarkar Beatrice Tassone Soumitra Ghosh Andrea Clocchiatti Sandro Goruppi Pino Bordignon Paris Jafari Fabio Tordini Thomas Lunardi Wolfram Hoetzenecker Victor Neel Joachim Lingner G. Paolo Dotto |
author_sort |
Giulia Bottoni |
title |
CSL controls telomere maintenance and genome stability in human dermal fibroblasts |
title_short |
CSL controls telomere maintenance and genome stability in human dermal fibroblasts |
title_full |
CSL controls telomere maintenance and genome stability in human dermal fibroblasts |
title_fullStr |
CSL controls telomere maintenance and genome stability in human dermal fibroblasts |
title_full_unstemmed |
CSL controls telomere maintenance and genome stability in human dermal fibroblasts |
title_sort |
csl controls telomere maintenance and genome stability in human dermal fibroblasts |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/82b5056962d14041aae036cba6d017e3 |
work_keys_str_mv |
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