ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON.
The inflammation is a multifactorial and highly regulated process associated to several chronic and degenerative diseases. Due to a lot of inflammatory process are sometimes characterized by oxidative stress, it has been demonstrated that antioxidants are useful as anti-inflammatory agents. The spec...
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Universidad de Antioquia
2011
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oai:doaj.org-article:82c9c36a2f614800a02003bc3f7a306d2021-11-19T04:14:11ZANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON.0121-40042145-2660https://doaj.org/article/82c9c36a2f614800a02003bc3f7a306d2011-05-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/6603https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660The inflammation is a multifactorial and highly regulated process associated to several chronic and degenerative diseases. Due to a lot of inflammatory process are sometimes characterized by oxidative stress, it has been demonstrated that antioxidants are useful as anti-inflammatory agents. The species Phenax rugosus (Poir.) Wedd and Tabebuia chrysanta G. Nicholson are used in the “Eje Cafetero” of Colombia by their antiinfeccious and immunomodulatory properties. In this work we evaluate in vivo anti-inflammatory and in vitro antioxidant properties of these plant species. We use two acute inflammation models: TPA-induced mouse ear oedema and carrageenan-induced rat paw oedema. In vitro antioxidant activity is evaluated against hydroxyl, peroxyl and superoxide radicals. The aquose extract of Phenax rugosus is promising because of their anti-inflammatory and antioxidant activities. These results are a rational for ethnopharmacological use of these plant species.Luis Fernando OSPINA GiraldoDiana M. ARAGÓNNadezdha E. VERGELGustavo ISAZAJorge E. PEREZUniversidad de AntioquiaarticlePhenax rugosusTabebuia chrysanthareactive oxygen speciesinflammation.Food processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 18, Iss 1 (2011) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Phenax rugosus Tabebuia chrysantha reactive oxygen species inflammation. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 |
spellingShingle |
Phenax rugosus Tabebuia chrysantha reactive oxygen species inflammation. Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 Luis Fernando OSPINA Giraldo Diana M. ARAGÓN Nadezdha E. VERGEL Gustavo ISAZA Jorge E. PEREZ ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON. |
description |
The inflammation is a multifactorial and highly regulated process associated to several chronic and degenerative diseases. Due to a lot of inflammatory process are sometimes characterized by oxidative stress, it has been demonstrated that antioxidants are useful as anti-inflammatory agents. The species Phenax rugosus (Poir.) Wedd and Tabebuia chrysanta G. Nicholson are used in the “Eje Cafetero” of Colombia by their antiinfeccious and immunomodulatory properties. In this work we evaluate in vivo anti-inflammatory and in vitro antioxidant properties of these plant species. We use two acute inflammation models: TPA-induced mouse ear oedema and carrageenan-induced rat paw oedema. In vitro antioxidant activity is evaluated against hydroxyl, peroxyl and superoxide radicals. The aquose extract of Phenax rugosus is promising because of their anti-inflammatory and antioxidant activities. These results are a rational for ethnopharmacological use of these plant species. |
format |
article |
author |
Luis Fernando OSPINA Giraldo Diana M. ARAGÓN Nadezdha E. VERGEL Gustavo ISAZA Jorge E. PEREZ |
author_facet |
Luis Fernando OSPINA Giraldo Diana M. ARAGÓN Nadezdha E. VERGEL Gustavo ISAZA Jorge E. PEREZ |
author_sort |
Luis Fernando OSPINA Giraldo |
title |
ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON. |
title_short |
ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON. |
title_full |
ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON. |
title_fullStr |
ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON. |
title_full_unstemmed |
ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON. |
title_sort |
anti-inflammatory and antioxidant activities of <i>phenax rugosus</i> (poir.) wedd and <i>tabebuia chrysanta</i> g. nicholson. |
publisher |
Universidad de Antioquia |
publishDate |
2011 |
url |
https://doaj.org/article/82c9c36a2f614800a02003bc3f7a306d |
work_keys_str_mv |
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