ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON.

The inflammation is a multifactorial and highly regulated process associated to several chronic and degenerative diseases. Due to a lot of inflammatory process are sometimes characterized by oxidative stress, it has been demonstrated that antioxidants are useful as anti-inflammatory agents. The spec...

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Autores principales: Luis Fernando OSPINA Giraldo, Diana M. ARAGÓN, Nadezdha E. VERGEL, Gustavo ISAZA, Jorge E. PEREZ
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Publicado: Universidad de Antioquia 2011
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spelling oai:doaj.org-article:82c9c36a2f614800a02003bc3f7a306d2021-11-19T04:14:11ZANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON.0121-40042145-2660https://doaj.org/article/82c9c36a2f614800a02003bc3f7a306d2011-05-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/6603https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660The inflammation is a multifactorial and highly regulated process associated to several chronic and degenerative diseases. Due to a lot of inflammatory process are sometimes characterized by oxidative stress, it has been demonstrated that antioxidants are useful as anti-inflammatory agents. The species Phenax rugosus (Poir.) Wedd and Tabebuia chrysanta G. Nicholson are used in the “Eje Cafetero” of Colombia by their antiinfeccious and immunomodulatory properties. In this work we evaluate in vivo anti-inflammatory and in vitro antioxidant properties of these plant species. We use two acute inflammation models: TPA-induced mouse ear oedema and carrageenan-induced rat paw oedema. In vitro antioxidant activity is evaluated against hydroxyl, peroxyl and superoxide radicals. The aquose extract of Phenax rugosus is promising because of their anti-inflammatory and antioxidant activities. These results are a rational for ethnopharmacological use of these plant species.Luis Fernando OSPINA GiraldoDiana M. ARAGÓNNadezdha E. VERGELGustavo ISAZAJorge E. PEREZUniversidad de AntioquiaarticlePhenax rugosusTabebuia chrysanthareactive oxygen speciesinflammation.Food processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 18, Iss 1 (2011)
institution DOAJ
collection DOAJ
language EN
topic Phenax rugosus
Tabebuia chrysantha
reactive oxygen species
inflammation.
Food processing and manufacture
TP368-456
Pharmaceutical industry
HD9665-9675
spellingShingle Phenax rugosus
Tabebuia chrysantha
reactive oxygen species
inflammation.
Food processing and manufacture
TP368-456
Pharmaceutical industry
HD9665-9675
Luis Fernando OSPINA Giraldo
Diana M. ARAGÓN
Nadezdha E. VERGEL
Gustavo ISAZA
Jorge E. PEREZ
ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON.
description The inflammation is a multifactorial and highly regulated process associated to several chronic and degenerative diseases. Due to a lot of inflammatory process are sometimes characterized by oxidative stress, it has been demonstrated that antioxidants are useful as anti-inflammatory agents. The species Phenax rugosus (Poir.) Wedd and Tabebuia chrysanta G. Nicholson are used in the “Eje Cafetero” of Colombia by their antiinfeccious and immunomodulatory properties. In this work we evaluate in vivo anti-inflammatory and in vitro antioxidant properties of these plant species. We use two acute inflammation models: TPA-induced mouse ear oedema and carrageenan-induced rat paw oedema. In vitro antioxidant activity is evaluated against hydroxyl, peroxyl and superoxide radicals. The aquose extract of Phenax rugosus is promising because of their anti-inflammatory and antioxidant activities. These results are a rational for ethnopharmacological use of these plant species.
format article
author Luis Fernando OSPINA Giraldo
Diana M. ARAGÓN
Nadezdha E. VERGEL
Gustavo ISAZA
Jorge E. PEREZ
author_facet Luis Fernando OSPINA Giraldo
Diana M. ARAGÓN
Nadezdha E. VERGEL
Gustavo ISAZA
Jorge E. PEREZ
author_sort Luis Fernando OSPINA Giraldo
title ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON.
title_short ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON.
title_full ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON.
title_fullStr ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON.
title_full_unstemmed ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES OF <I>PHENAX rugosus</I> (POIR.) WEDD AND <I>TABEBUIA chrysanta</I> G. NICHOLSON.
title_sort anti-inflammatory and antioxidant activities of <i>phenax rugosus</i> (poir.) wedd and <i>tabebuia chrysanta</i> g. nicholson.
publisher Universidad de Antioquia
publishDate 2011
url https://doaj.org/article/82c9c36a2f614800a02003bc3f7a306d
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