Aripiprazole for late-life schizophrenia

Jeffrey Rado, Philip G JanicakPsychiatric Clinical Research Center, Rush University Medical Center, Chicago, IL, USAAbstract: Antipsychotics are frequently used in elderly patients to treat a variety of conditions, including schizophrenia. While extensively studied for their impact in younger &s...

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Autores principales:	Jeffrey Rado, Philip G Janicak
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Aripiprazole Schizophrenia elderly Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/82cedea055084d7987558f126be3c376
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id	oai:doaj.org-article:82cedea055084d7987558f126be3c376
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spelling	oai:doaj.org-article:82cedea055084d7987558f126be3c3762021-12-02T06:20:40ZAripiprazole for late-life schizophrenia1178-1998https://doaj.org/article/82cedea055084d7987558f126be3c3762010-08-01T00:00:00Zhttps://www.dovepress.com/aripiprazole-for-late-life-schizophrenia-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Jeffrey Rado, Philip G JanicakPsychiatric Clinical Research Center, Rush University Medical Center, Chicago, IL, USAAbstract: Antipsychotics are frequently used in elderly patients to treat a variety of conditions, including schizophrenia. While extensively studied for their impact in younger populations, there is comparatively limited evidence about the effectiveness of these agents in older patients. Further complicating this situation are the high co-morbidity rates (both psychiatric and medical) in the elderly; age-related changes in pharmacokinetics leading to a heightened proclivity for adverse effects; and the potential for multiple, clinically relevant drug interactions. With this background in mind, we review diagnostic and treatment-related issues specific to elderly patients suffering from schizophrenia and other psychotic conditions, focusing on the potential role of aripiprazole.Keywords: aripiprazole, schizophrenia, elderly, dopamine partial antagonistJeffrey RadoPhilip G JanicakDove Medical PressarticleAripiprazoleSchizophreniaelderlyGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 5, Pp 253-258 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Aripiprazole Schizophrenia elderly Geriatrics RC952-954.6
spellingShingle	Aripiprazole Schizophrenia elderly Geriatrics RC952-954.6 Jeffrey Rado Philip G Janicak Aripiprazole for late-life schizophrenia
description	Jeffrey Rado, Philip G JanicakPsychiatric Clinical Research Center, Rush University Medical Center, Chicago, IL, USAAbstract: Antipsychotics are frequently used in elderly patients to treat a variety of conditions, including schizophrenia. While extensively studied for their impact in younger populations, there is comparatively limited evidence about the effectiveness of these agents in older patients. Further complicating this situation are the high co-morbidity rates (both psychiatric and medical) in the elderly; age-related changes in pharmacokinetics leading to a heightened proclivity for adverse effects; and the potential for multiple, clinically relevant drug interactions. With this background in mind, we review diagnostic and treatment-related issues specific to elderly patients suffering from schizophrenia and other psychotic conditions, focusing on the potential role of aripiprazole.Keywords: aripiprazole, schizophrenia, elderly, dopamine partial antagonist
format	article
author	Jeffrey Rado Philip G Janicak
author_facet	Jeffrey Rado Philip G Janicak
author_sort	Jeffrey Rado
title	Aripiprazole for late-life schizophrenia
title_short	Aripiprazole for late-life schizophrenia
title_full	Aripiprazole for late-life schizophrenia
title_fullStr	Aripiprazole for late-life schizophrenia
title_full_unstemmed	Aripiprazole for late-life schizophrenia
title_sort	aripiprazole for late-life schizophrenia
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/82cedea055084d7987558f126be3c376
work_keys_str_mv	AT jeffreyrado aripiprazoleforlatelifeschizophrenia AT philipgjanicak aripiprazoleforlatelifeschizophrenia
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Aripiprazole for late-life schizophrenia

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