Epileptic and cognitive changes in children with cerebral palsy: an Egyptian study

Hamdy N El-Tallawy, Wafaa MA Farghaly, Ghaydaa A Shehata, Reda Badry, Tarek A Rageh Department of Neurology, Assiut University Hospitals, Assiut, Egypt Background: Cerebral palsy (CP) is the most frequent cause of motor handicap among children. Aim of the study: We aim to study the relation of epi...

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Autores principales:	El-Tallawy HN, Farghaly WMA, Shehata GA, Badry R, Rageh TA
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/82d024078e6b44fdb90eb8af47c765b2
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spelling	oai:doaj.org-article:82d024078e6b44fdb90eb8af47c765b22021-12-02T06:00:40ZEpileptic and cognitive changes in children with cerebral palsy: an Egyptian study1178-2021https://doaj.org/article/82d024078e6b44fdb90eb8af47c765b22014-05-01T00:00:00Zhttp://www.dovepress.com/epileptic-and-cognitive-changes-in-children-with-cerebral-palsy-an-egy-a17069https://doaj.org/toc/1178-2021 Hamdy N El-Tallawy, Wafaa MA Farghaly, Ghaydaa A Shehata, Reda Badry, Tarek A Rageh Department of Neurology, Assiut University Hospitals, Assiut, Egypt Background: Cerebral palsy (CP) is the most frequent cause of motor handicap among children. Aim of the study: We aim to study the relation of epilepsy in children with CP to various risk factors that affect the development of seizures. Patients and methods: In a cross-sectional, descriptive, population-based, case-control study, 98 children with CP (48 children with CP with epilepsy, and 50 children with CP without epilepsy) were compared with 180 children without CP or seizures. The children lived in two regions in Egypt: the Al-Kharga District–New Valley and El-Quseir city–Red Sea. These cases were subjected to meticulous neurological assessment, brain magnetic resonance imaging, electroencephalography, and Stanford-Binet (4th edition) examination. Multinomial logistic regression was used to assess the risk factors. Results: Epilepsy was diagnosed in 48.9% of all cases of CP. Mental subnormality was observed more frequently in children with epilepsy than in those without epilepsy (84.6% versus 66.7%). The frequency of epilepsy was highest in patients with the spastic quadriplegic type of illness (58.3%). Multinomial logistic regression revealed that prematurity (<32 weeks of pregnancy), low birth weight (<2.5 kg at birth), neonatal seizures, jaundice, and cyanosis were significantly associated with CP with epilepsy. Conclusion: CP is associated with a high percentage of seizure disorders. Prematurity, low birth weight, neonatal seizures, cyanosis, and jaundice are significant risk factors among patients with CP with epilepsy compared to patients with CP without epilepsy or a healthy control group. Keywords: cerebral palsy, epilepsy, risk factors, EgyptEl-Tallawy HNFarghaly WMAShehata GABadry RRageh TADove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2014, Iss default, Pp 971-975 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 El-Tallawy HN Farghaly WMA Shehata GA Badry R Rageh TA Epileptic and cognitive changes in children with cerebral palsy: an Egyptian study
description	Hamdy N El-Tallawy, Wafaa MA Farghaly, Ghaydaa A Shehata, Reda Badry, Tarek A Rageh Department of Neurology, Assiut University Hospitals, Assiut, Egypt Background: Cerebral palsy (CP) is the most frequent cause of motor handicap among children. Aim of the study: We aim to study the relation of epilepsy in children with CP to various risk factors that affect the development of seizures. Patients and methods: In a cross-sectional, descriptive, population-based, case-control study, 98 children with CP (48 children with CP with epilepsy, and 50 children with CP without epilepsy) were compared with 180 children without CP or seizures. The children lived in two regions in Egypt: the Al-Kharga District–New Valley and El-Quseir city–Red Sea. These cases were subjected to meticulous neurological assessment, brain magnetic resonance imaging, electroencephalography, and Stanford-Binet (4th edition) examination. Multinomial logistic regression was used to assess the risk factors. Results: Epilepsy was diagnosed in 48.9% of all cases of CP. Mental subnormality was observed more frequently in children with epilepsy than in those without epilepsy (84.6% versus 66.7%). The frequency of epilepsy was highest in patients with the spastic quadriplegic type of illness (58.3%). Multinomial logistic regression revealed that prematurity (<32 weeks of pregnancy), low birth weight (<2.5 kg at birth), neonatal seizures, jaundice, and cyanosis were significantly associated with CP with epilepsy. Conclusion: CP is associated with a high percentage of seizure disorders. Prematurity, low birth weight, neonatal seizures, cyanosis, and jaundice are significant risk factors among patients with CP with epilepsy compared to patients with CP without epilepsy or a healthy control group. Keywords: cerebral palsy, epilepsy, risk factors, Egypt
format	article
author	El-Tallawy HN Farghaly WMA Shehata GA Badry R Rageh TA
author_facet	El-Tallawy HN Farghaly WMA Shehata GA Badry R Rageh TA
author_sort	El-Tallawy HN
title	Epileptic and cognitive changes in children with cerebral palsy: an Egyptian study
title_short	Epileptic and cognitive changes in children with cerebral palsy: an Egyptian study
title_full	Epileptic and cognitive changes in children with cerebral palsy: an Egyptian study
title_fullStr	Epileptic and cognitive changes in children with cerebral palsy: an Egyptian study
title_full_unstemmed	Epileptic and cognitive changes in children with cerebral palsy: an Egyptian study
title_sort	epileptic and cognitive changes in children with cerebral palsy: an egyptian study
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/82d024078e6b44fdb90eb8af47c765b2
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_version_	1718400118386851840

Epileptic and cognitive changes in children with cerebral palsy: an Egyptian study

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