TOXIC LIVER DAMAGE IN ACUTE PHASE OF ETHANOL INTOXICATION AND ITS EXPERIMENTAL CORRECTION WITH CHELATE ZINC COMPOUND

It was established, that ethanol in the dose of 12 g/kg in experimental animals (white non-inbred male rats) had. expressed damaging effect on the liver, that is shown in statistically significant increase of activity of hepatic enzymes (alanine aminotransferase, alkaline phosphatase), hypoglycemia,...

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Autores principales:	A. V. Mashanov, B. Ya. Vlasov, G. G. Yushkov, V. V. Benemanskiy
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	2 8 9-тригидроцинкатран toxic liver damage acute ethanol poisoning alcohol dehydrogenase 9-trihydrozincatrane Science Q
Acceso en línea:	https://doaj.org/article/82d9a007c47b4db7ab966717ad5f3893
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id	oai:doaj.org-article:82d9a007c47b4db7ab966717ad5f3893
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spelling	oai:doaj.org-article:82d9a007c47b4db7ab966717ad5f38932021-11-23T06:14:23ZTOXIC LIVER DAMAGE IN ACUTE PHASE OF ETHANOL INTOXICATION AND ITS EXPERIMENTAL CORRECTION WITH CHELATE ZINC COMPOUND2541-94202587-9596https://doaj.org/article/82d9a007c47b4db7ab966717ad5f38932012-07-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1056https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596It was established, that ethanol in the dose of 12 g/kg in experimental animals (white non-inbred male rats) had. expressed damaging effect on the liver, that is shown in statistically significant increase of activity of hepatic enzymes (alanine aminotransferase, alkaline phosphatase), hypoglycemia, development of albuminous and. hydropic degeneration. It is proved, that application of new chelate zinc (2,8,9-trigidrotsinkatrane) in experimental correction of acute ethanol poisoning promotes reduction of metabolic and morphological derangements.A. V. MashanovB. Ya. VlasovG. G. YushkovV. V. BenemanskiyScientific Сentre for Family Health and Human Reproduction Problemsarticle289-тригидроцинкатранtoxic liver damageacute ethanol poisoningalcohol dehydrogenase289-trihydrozincatraneScienceQRUActa Biomedica Scientifica, Vol 0, Iss 4(2), Pp 179-184 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	2 8 9-тригидроцинкатран toxic liver damage acute ethanol poisoning alcohol dehydrogenase 2 8 9-trihydrozincatrane Science Q
spellingShingle	2 8 9-тригидроцинкатран toxic liver damage acute ethanol poisoning alcohol dehydrogenase 2 8 9-trihydrozincatrane Science Q A. V. Mashanov B. Ya. Vlasov G. G. Yushkov V. V. Benemanskiy TOXIC LIVER DAMAGE IN ACUTE PHASE OF ETHANOL INTOXICATION AND ITS EXPERIMENTAL CORRECTION WITH CHELATE ZINC COMPOUND
description	It was established, that ethanol in the dose of 12 g/kg in experimental animals (white non-inbred male rats) had. expressed damaging effect on the liver, that is shown in statistically significant increase of activity of hepatic enzymes (alanine aminotransferase, alkaline phosphatase), hypoglycemia, development of albuminous and. hydropic degeneration. It is proved, that application of new chelate zinc (2,8,9-trigidrotsinkatrane) in experimental correction of acute ethanol poisoning promotes reduction of metabolic and morphological derangements.
format	article
author	A. V. Mashanov B. Ya. Vlasov G. G. Yushkov V. V. Benemanskiy
author_facet	A. V. Mashanov B. Ya. Vlasov G. G. Yushkov V. V. Benemanskiy
author_sort	A. V. Mashanov
title	TOXIC LIVER DAMAGE IN ACUTE PHASE OF ETHANOL INTOXICATION AND ITS EXPERIMENTAL CORRECTION WITH CHELATE ZINC COMPOUND
title_short	TOXIC LIVER DAMAGE IN ACUTE PHASE OF ETHANOL INTOXICATION AND ITS EXPERIMENTAL CORRECTION WITH CHELATE ZINC COMPOUND
title_full	TOXIC LIVER DAMAGE IN ACUTE PHASE OF ETHANOL INTOXICATION AND ITS EXPERIMENTAL CORRECTION WITH CHELATE ZINC COMPOUND
title_fullStr	TOXIC LIVER DAMAGE IN ACUTE PHASE OF ETHANOL INTOXICATION AND ITS EXPERIMENTAL CORRECTION WITH CHELATE ZINC COMPOUND
title_full_unstemmed	TOXIC LIVER DAMAGE IN ACUTE PHASE OF ETHANOL INTOXICATION AND ITS EXPERIMENTAL CORRECTION WITH CHELATE ZINC COMPOUND
title_sort	toxic liver damage in acute phase of ethanol intoxication and its experimental correction with chelate zinc compound
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/82d9a007c47b4db7ab966717ad5f3893
work_keys_str_mv	AT avmashanov toxicliverdamageinacutephaseofethanolintoxicationanditsexperimentalcorrectionwithchelatezinccompound AT byavlasov toxicliverdamageinacutephaseofethanolintoxicationanditsexperimentalcorrectionwithchelatezinccompound AT ggyushkov toxicliverdamageinacutephaseofethanolintoxicationanditsexperimentalcorrectionwithchelatezinccompound AT vvbenemanskiy toxicliverdamageinacutephaseofethanolintoxicationanditsexperimentalcorrectionwithchelatezinccompound
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TOXIC LIVER DAMAGE IN ACUTE PHASE OF ETHANOL INTOXICATION AND ITS EXPERIMENTAL CORRECTION WITH CHELATE ZINC COMPOUND

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