Multi-omics profiling of primary small cell carcinoma of the esophagus reveals RB1 disruption and additional molecular subtypes

Multi-omics profiling of primary small cell carcinoma of the esophagus reveals RB1 disruption and additional molecular subtypes

Primary small cell carcinoma of the oesophagus has a poor prognosis, and has not been fully characterised molecularly. Here, the authors study the disease using multi-omics technology and find frequent RB1 disruptions and similarities to small cell lung cancer, opening potential therapeutic avenues.

Guardado en:
Detalles Bibliográficos
Autores principales: Renda Li, Zhenlin Yang, Fei Shao, Hong Cheng, Yaru Wen, Sijin Sun, Wei Guo, Zitong Li, Fan Zhang, Liyan Xue, Nan Bi, Jie Wang, Yingli Sun, Yin Li, Fengwei Tan, Qi Xue, Shugeng Gao, Susheng Shi, Yibo Gao, Jie He
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/82de6a19353d420ea06e6ba8c515d3bc
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/82de6a19353d420ea06e6ba8c515d3bc

Ejemplares similares