High-throughput interrogation of programmed ribosomal frameshifting in human cells
Programmed ribosomal frameshifting—the slippage of the ribosome to an alternative frame — is critical for viral replication and cellular processes. Here the authors present an approach that can assess the frameshifting potential of a sequence and elucidate the rules governing ribosomal frameshifting...
Saved in:
Main Authors: | Martin Mikl, Yitzhak Pilpel, Eran Segal |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/82e2217d97d24ceda90271fe670fb62c |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Dissecting splicing decisions and cell-to-cell variability with designed sequence libraries
by: Martin Mikl, et al.
Published: (2019) -
Thermodynamic control of −1 programmed ribosomal frameshifting
by: Lars V. Bock, et al.
Published: (2019) -
Protein-directed ribosomal frameshifting temporally regulates gene expression
by: Sawsan Napthine, et al.
Published: (2017) -
Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation
by: Gabriel Demo, et al.
Published: (2021) -
Interrogating cellular fate decisions with high-throughput arrays of multiplexed cellular communities
by: Sisi Chen, et al.
Published: (2016)