Impact of cavotricuspid isthmus depth on the ablation index for successful first-pass typical atrial flutter ablation

Abstract Cavotricuspid isthmus (CTI) linear ablation has been established as the treatment for typical atrial flutter. Recently, ablation index (AI) has emerged as a novel marker for estimating ablation lesions. We investigated the relationship between CTI depth and ablation parameters on the proced...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Manabu Kashiwagi, Akio Kuroi, Yosuke Katayama, Kosei Terada, Suwako Fujita, Takeshi Hozumi, Kunihiro Shimamura, Yasutsugu Shiono, Takashi Tanimoto, Takashi Kubo, Atsushi Tanaka, Takashi Akasaka
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/82e5e1120cdf4c8b9373dae5dbaa83fc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:82e5e1120cdf4c8b9373dae5dbaa83fc
record_format	dspace
spelling	oai:doaj.org-article:82e5e1120cdf4c8b9373dae5dbaa83fc2021-11-21T12:16:35ZImpact of cavotricuspid isthmus depth on the ablation index for successful first-pass typical atrial flutter ablation10.1038/s41598-021-01846-72045-2322https://doaj.org/article/82e5e1120cdf4c8b9373dae5dbaa83fc2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-01846-7https://doaj.org/toc/2045-2322Abstract Cavotricuspid isthmus (CTI) linear ablation has been established as the treatment for typical atrial flutter. Recently, ablation index (AI) has emerged as a novel marker for estimating ablation lesions. We investigated the relationship between CTI depth and ablation parameters on the procedural results of typical atrial flutter ablation. A total of 107 patients who underwent CTI ablation were retrospectively enrolled in this study. All patients underwent computed tomography before catheter ablation. From the receiver-operating curve, the best cut-off value of CTI depth was < 4.1 mm to predict first-pass success. Although the average AI was not different between deep CTI (DC; CTI depth ≥ 4.1) and shallow CTI (SC; CTI depth < 4.1), DC required a longer ablation time and showed a lower first-pass success rate (p < 0.01). In addition, the catheter inversion technique was more frequently required in the DC (p < 0.01). The lowest AI sites of the first-pass CTI line were determined in both the ventricular (2/3 segment of CTI) and inferior vena cava (IVC, 1/3 segment of CTI) sides. The best cut-off values of the weakest AIs at the ventricular and IVC sides for predicting first-pass success were > 420 and > 386, respectively. Among patients with these cut-off values, the first-pass success rate was 89% in the SC and 50% in the DC (p < 0.01). Although ablation parameters were not significantly different, the first-pass success rate was lower in the DC than in the SC. Further investigation might be required for better outcomes in deep CTIs.Manabu KashiwagiAkio KuroiYosuke KatayamaKosei TeradaSuwako FujitaTakeshi HozumiKunihiro ShimamuraYasutsugu ShionoTakashi TanimotoTakashi KuboAtsushi TanakaTakashi AkasakaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Manabu Kashiwagi Akio Kuroi Yosuke Katayama Kosei Terada Suwako Fujita Takeshi Hozumi Kunihiro Shimamura Yasutsugu Shiono Takashi Tanimoto Takashi Kubo Atsushi Tanaka Takashi Akasaka Impact of cavotricuspid isthmus depth on the ablation index for successful first-pass typical atrial flutter ablation
description	Abstract Cavotricuspid isthmus (CTI) linear ablation has been established as the treatment for typical atrial flutter. Recently, ablation index (AI) has emerged as a novel marker for estimating ablation lesions. We investigated the relationship between CTI depth and ablation parameters on the procedural results of typical atrial flutter ablation. A total of 107 patients who underwent CTI ablation were retrospectively enrolled in this study. All patients underwent computed tomography before catheter ablation. From the receiver-operating curve, the best cut-off value of CTI depth was < 4.1 mm to predict first-pass success. Although the average AI was not different between deep CTI (DC; CTI depth ≥ 4.1) and shallow CTI (SC; CTI depth < 4.1), DC required a longer ablation time and showed a lower first-pass success rate (p < 0.01). In addition, the catheter inversion technique was more frequently required in the DC (p < 0.01). The lowest AI sites of the first-pass CTI line were determined in both the ventricular (2/3 segment of CTI) and inferior vena cava (IVC, 1/3 segment of CTI) sides. The best cut-off values of the weakest AIs at the ventricular and IVC sides for predicting first-pass success were > 420 and > 386, respectively. Among patients with these cut-off values, the first-pass success rate was 89% in the SC and 50% in the DC (p < 0.01). Although ablation parameters were not significantly different, the first-pass success rate was lower in the DC than in the SC. Further investigation might be required for better outcomes in deep CTIs.
format	article
author	Manabu Kashiwagi Akio Kuroi Yosuke Katayama Kosei Terada Suwako Fujita Takeshi Hozumi Kunihiro Shimamura Yasutsugu Shiono Takashi Tanimoto Takashi Kubo Atsushi Tanaka Takashi Akasaka
author_facet	Manabu Kashiwagi Akio Kuroi Yosuke Katayama Kosei Terada Suwako Fujita Takeshi Hozumi Kunihiro Shimamura Yasutsugu Shiono Takashi Tanimoto Takashi Kubo Atsushi Tanaka Takashi Akasaka
author_sort	Manabu Kashiwagi
title	Impact of cavotricuspid isthmus depth on the ablation index for successful first-pass typical atrial flutter ablation
title_short	Impact of cavotricuspid isthmus depth on the ablation index for successful first-pass typical atrial flutter ablation
title_full	Impact of cavotricuspid isthmus depth on the ablation index for successful first-pass typical atrial flutter ablation
title_fullStr	Impact of cavotricuspid isthmus depth on the ablation index for successful first-pass typical atrial flutter ablation
title_full_unstemmed	Impact of cavotricuspid isthmus depth on the ablation index for successful first-pass typical atrial flutter ablation
title_sort	impact of cavotricuspid isthmus depth on the ablation index for successful first-pass typical atrial flutter ablation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/82e5e1120cdf4c8b9373dae5dbaa83fc
work_keys_str_mv	AT manabukashiwagi impactofcavotricuspidisthmusdepthontheablationindexforsuccessfulfirstpasstypicalatrialflutterablation AT akiokuroi impactofcavotricuspidisthmusdepthontheablationindexforsuccessfulfirstpasstypicalatrialflutterablation AT yosukekatayama impactofcavotricuspidisthmusdepthontheablationindexforsuccessfulfirstpasstypicalatrialflutterablation AT koseiterada impactofcavotricuspidisthmusdepthontheablationindexforsuccessfulfirstpasstypicalatrialflutterablation AT suwakofujita impactofcavotricuspidisthmusdepthontheablationindexforsuccessfulfirstpasstypicalatrialflutterablation AT takeshihozumi impactofcavotricuspidisthmusdepthontheablationindexforsuccessfulfirstpasstypicalatrialflutterablation AT kunihiroshimamura impactofcavotricuspidisthmusdepthontheablationindexforsuccessfulfirstpasstypicalatrialflutterablation AT yasutsugushiono impactofcavotricuspidisthmusdepthontheablationindexforsuccessfulfirstpasstypicalatrialflutterablation AT takashitanimoto impactofcavotricuspidisthmusdepthontheablationindexforsuccessfulfirstpasstypicalatrialflutterablation AT takashikubo impactofcavotricuspidisthmusdepthontheablationindexforsuccessfulfirstpasstypicalatrialflutterablation AT atsushitanaka impactofcavotricuspidisthmusdepthontheablationindexforsuccessfulfirstpasstypicalatrialflutterablation AT takashiakasaka impactofcavotricuspidisthmusdepthontheablationindexforsuccessfulfirstpasstypicalatrialflutterablation
_version_	1718419133591191552

Impact of cavotricuspid isthmus depth on the ablation index for successful first-pass typical atrial flutter ablation

Ejemplares similares