Pathophysiology of Cerebral Edema—A Comprehensive Review

Cerebral edema is a condition where an excess of cerebral water accumulates due to primary neurological or non-neurological causes. Cerebral edema complicates many brain pathologies causing additional injury often in excess of the original neurological insult. Classic descriptions divide cerebral ed...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Tara Dalby, Elyana Wohl, Michael Dinsmore, Zoe Unger, Tumul Chowdhury, Lakshmikumar Venkatraghavan
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2021
Materias:	cerebral edema blood–brain barrier aquaporins Anesthesiology RD78.3-87.3
Acceso en línea:	https://doaj.org/article/82ef7fb46b96459f8b269da41c7327e6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:82ef7fb46b96459f8b269da41c7327e6
record_format	dspace
spelling	oai:doaj.org-article:82ef7fb46b96459f8b269da41c7327e62021-12-02T23:53:13ZPathophysiology of Cerebral Edema—A Comprehensive Review2348-05482348-926X10.1055/s-0040-1721165https://doaj.org/article/82ef7fb46b96459f8b269da41c7327e62021-09-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1721165https://doaj.org/toc/2348-0548https://doaj.org/toc/2348-926XCerebral edema is a condition where an excess of cerebral water accumulates due to primary neurological or non-neurological causes. Cerebral edema complicates many brain pathologies causing additional injury often in excess of the original neurological insult. Classic descriptions divide cerebral edema into cytotoxic, vasogenic, interstitial, and osmotic subtypes. The interplay of different mechanisms is important in the clinical manifestations. Recent research has advanced our understanding of the molecular pathophysiology of cerebral edema, exposing the central role of aquaporins and specific ion channels. The aim of this review is to provide a comprehensive overview of the molecular pathophysiology of cerebral edema including unique disease specific mechanisms.Tara DalbyElyana WohlMichael DinsmoreZoe UngerTumul ChowdhuryLakshmikumar VenkatraghavanThieme Medical and Scientific Publishers Pvt. Ltd.articlecerebral edemablood–brain barrieraquaporinsAnesthesiologyRD78.3-87.3ENJournal of Neuroanaesthesiology and Critical Care, Vol 08, Iss 03, Pp 163-172 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cerebral edema blood–brain barrier aquaporins Anesthesiology RD78.3-87.3
spellingShingle	cerebral edema blood–brain barrier aquaporins Anesthesiology RD78.3-87.3 Tara Dalby Elyana Wohl Michael Dinsmore Zoe Unger Tumul Chowdhury Lakshmikumar Venkatraghavan Pathophysiology of Cerebral Edema—A Comprehensive Review
description	Cerebral edema is a condition where an excess of cerebral water accumulates due to primary neurological or non-neurological causes. Cerebral edema complicates many brain pathologies causing additional injury often in excess of the original neurological insult. Classic descriptions divide cerebral edema into cytotoxic, vasogenic, interstitial, and osmotic subtypes. The interplay of different mechanisms is important in the clinical manifestations. Recent research has advanced our understanding of the molecular pathophysiology of cerebral edema, exposing the central role of aquaporins and specific ion channels. The aim of this review is to provide a comprehensive overview of the molecular pathophysiology of cerebral edema including unique disease specific mechanisms.
format	article
author	Tara Dalby Elyana Wohl Michael Dinsmore Zoe Unger Tumul Chowdhury Lakshmikumar Venkatraghavan
author_facet	Tara Dalby Elyana Wohl Michael Dinsmore Zoe Unger Tumul Chowdhury Lakshmikumar Venkatraghavan
author_sort	Tara Dalby
title	Pathophysiology of Cerebral Edema—A Comprehensive Review
title_short	Pathophysiology of Cerebral Edema—A Comprehensive Review
title_full	Pathophysiology of Cerebral Edema—A Comprehensive Review
title_fullStr	Pathophysiology of Cerebral Edema—A Comprehensive Review
title_full_unstemmed	Pathophysiology of Cerebral Edema—A Comprehensive Review
title_sort	pathophysiology of cerebral edema—a comprehensive review
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2021
url	https://doaj.org/article/82ef7fb46b96459f8b269da41c7327e6
work_keys_str_mv	AT taradalby pathophysiologyofcerebraledemaacomprehensivereview AT elyanawohl pathophysiologyofcerebraledemaacomprehensivereview AT michaeldinsmore pathophysiologyofcerebraledemaacomprehensivereview AT zoeunger pathophysiologyofcerebraledemaacomprehensivereview AT tumulchowdhury pathophysiologyofcerebraledemaacomprehensivereview AT lakshmikumarvenkatraghavan pathophysiologyofcerebraledemaacomprehensivereview
_version_	1718373998802239488

Pathophysiology of Cerebral Edema—A Comprehensive Review

Ejemplares similares