Copy number variation of the beta-defensin genes in europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma.
Lung function measures are heritable, predict mortality and are relevant in diagnosis of chronic obstructive pulmonary disease (COPD). COPD and asthma are diseases of the airways with major public health impacts and each have a heritable component. Genome-wide association studies of SNPs have reveal...
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Autores principales: | Louise V Wain, Linda Odenthal-Hesse, Razan Abujaber, Ian Sayers, Caroline Beardsmore, Erol A Gaillard, Sally Chappell, Cristian M Dogaru, Tricia McKeever, Tamar Guetta-Baranes, Noor Kalsheker, Claudia E Kuehni, Ian P Hall, Martin D Tobin, Edward J Hollox |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/82f2d49534d3480ea8d9902b1ed39aec |
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