Association between winter cold spells and acute myocardial infarction in Lithuania 2000–2015

Abstract Acute myocardial infarction (AMI) is a major public health problem. Cold winter weather increases the risk of AMI, but factors influencing susceptibility are poorly known. We conducted an individual-level case-crossover study of the associations between winter cold spells and the risk of AM...

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Autores principales:	Vidmantas Vaičiulis, Jouni J. K. Jaakkola, Ričardas Radišauskas, Abdonas Tamošiūnas, Dalia Lukšienė, Niilo R. I. Ryti
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/82f6e4037d46415e80e08e2188ecd47c
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spelling	oai:doaj.org-article:82f6e4037d46415e80e08e2188ecd47c2021-12-02T15:09:15ZAssociation between winter cold spells and acute myocardial infarction in Lithuania 2000–201510.1038/s41598-021-96366-92045-2322https://doaj.org/article/82f6e4037d46415e80e08e2188ecd47c2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-96366-9https://doaj.org/toc/2045-2322Abstract Acute myocardial infarction (AMI) is a major public health problem. Cold winter weather increases the risk of AMI, but factors influencing susceptibility are poorly known. We conducted an individual-level case-crossover study of the associations between winter cold spells and the risk of AMI, with special focus on survival at 28 days and effect modification by age and sex. All 16,071 adult cases of AMI among the residents of the city of Kaunas in Lithuania in 2000–2015 were included in the study. Cold weather was statistically defined using the 5th percentile of frequency distribution of daily mean temperatures over the winter months. According to conditional logistic regression controlling for time-varying and time-invariant confounders, each additional cold spell day during the week preceding AMI increased the risk of AMI by 5% (95% CI 1–9%). For nonfatal and fatal cases, the risk increase per each additional cold spell day was 5% (95% CI 1–9%) and 6% (95% CI − 2–13%), respectively. The effect estimate was greater for men (OR 1.07, 95% CI 1.02–1.12) than for women (OR 1.02, 95% CI 0.97–1.08), but there was no evidence of effect modification by age. Evidence on factors increasing susceptibility is critical for targeted cold weather planning.Vidmantas VaičiulisJouni J. K. JaakkolaRičardas RadišauskasAbdonas TamošiūnasDalia LukšienėNiilo R. I. RytiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Vidmantas Vaičiulis Jouni J. K. Jaakkola Ričardas Radišauskas Abdonas Tamošiūnas Dalia Lukšienė Niilo R. I. Ryti Association between winter cold spells and acute myocardial infarction in Lithuania 2000–2015
description	Abstract Acute myocardial infarction (AMI) is a major public health problem. Cold winter weather increases the risk of AMI, but factors influencing susceptibility are poorly known. We conducted an individual-level case-crossover study of the associations between winter cold spells and the risk of AMI, with special focus on survival at 28 days and effect modification by age and sex. All 16,071 adult cases of AMI among the residents of the city of Kaunas in Lithuania in 2000–2015 were included in the study. Cold weather was statistically defined using the 5th percentile of frequency distribution of daily mean temperatures over the winter months. According to conditional logistic regression controlling for time-varying and time-invariant confounders, each additional cold spell day during the week preceding AMI increased the risk of AMI by 5% (95% CI 1–9%). For nonfatal and fatal cases, the risk increase per each additional cold spell day was 5% (95% CI 1–9%) and 6% (95% CI − 2–13%), respectively. The effect estimate was greater for men (OR 1.07, 95% CI 1.02–1.12) than for women (OR 1.02, 95% CI 0.97–1.08), but there was no evidence of effect modification by age. Evidence on factors increasing susceptibility is critical for targeted cold weather planning.
format	article
author	Vidmantas Vaičiulis Jouni J. K. Jaakkola Ričardas Radišauskas Abdonas Tamošiūnas Dalia Lukšienė Niilo R. I. Ryti
author_facet	Vidmantas Vaičiulis Jouni J. K. Jaakkola Ričardas Radišauskas Abdonas Tamošiūnas Dalia Lukšienė Niilo R. I. Ryti
author_sort	Vidmantas Vaičiulis
title	Association between winter cold spells and acute myocardial infarction in Lithuania 2000–2015
title_short	Association between winter cold spells and acute myocardial infarction in Lithuania 2000–2015
title_full	Association between winter cold spells and acute myocardial infarction in Lithuania 2000–2015
title_fullStr	Association between winter cold spells and acute myocardial infarction in Lithuania 2000–2015
title_full_unstemmed	Association between winter cold spells and acute myocardial infarction in Lithuania 2000–2015
title_sort	association between winter cold spells and acute myocardial infarction in lithuania 2000–2015
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/82f6e4037d46415e80e08e2188ecd47c
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Association between winter cold spells and acute myocardial infarction in Lithuania 2000–2015

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