Regulation of cell-to-cell variability in divergent gene expression

Gene expression noise affects cell fitness and development. Here, Yan et al. show that co-regulated divergent gene pairs (DGPs) suppress uncorrelated gene expression noise due to more synchronized transcription firing, and differentially regulated DGPs enhance gene expression noise due to transcript...

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Autores principales:	Chao Yan, Shuyang Wu, Christopher Pocetti, Lu Bai
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/82f8729b4630411bb2cb3f9dd984475d
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spelling	oai:doaj.org-article:82f8729b4630411bb2cb3f9dd984475d2021-12-02T14:38:34ZRegulation of cell-to-cell variability in divergent gene expression10.1038/ncomms110992041-1723https://doaj.org/article/82f8729b4630411bb2cb3f9dd984475d2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11099https://doaj.org/toc/2041-1723Gene expression noise affects cell fitness and development. Here, Yan et al. show that co-regulated divergent gene pairs (DGPs) suppress uncorrelated gene expression noise due to more synchronized transcription firing, and differentially regulated DGPs enhance gene expression noise due to transcription leakage.Chao YanShuyang WuChristopher PocettiLu BaiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chao Yan Shuyang Wu Christopher Pocetti Lu Bai Regulation of cell-to-cell variability in divergent gene expression
description	Gene expression noise affects cell fitness and development. Here, Yan et al. show that co-regulated divergent gene pairs (DGPs) suppress uncorrelated gene expression noise due to more synchronized transcription firing, and differentially regulated DGPs enhance gene expression noise due to transcription leakage.
format	article
author	Chao Yan Shuyang Wu Christopher Pocetti Lu Bai
author_facet	Chao Yan Shuyang Wu Christopher Pocetti Lu Bai
author_sort	Chao Yan
title	Regulation of cell-to-cell variability in divergent gene expression
title_short	Regulation of cell-to-cell variability in divergent gene expression
title_full	Regulation of cell-to-cell variability in divergent gene expression
title_fullStr	Regulation of cell-to-cell variability in divergent gene expression
title_full_unstemmed	Regulation of cell-to-cell variability in divergent gene expression
title_sort	regulation of cell-to-cell variability in divergent gene expression
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/82f8729b4630411bb2cb3f9dd984475d
work_keys_str_mv	AT chaoyan regulationofcelltocellvariabilityindivergentgeneexpression AT shuyangwu regulationofcelltocellvariabilityindivergentgeneexpression AT christopherpocetti regulationofcelltocellvariabilityindivergentgeneexpression AT lubai regulationofcelltocellvariabilityindivergentgeneexpression
_version_	1718390961800740864

Regulation of cell-to-cell variability in divergent gene expression

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