Ribosome profiling at isoform level reveals evolutionary conserved impacts of differential splicing on the proteome

Ribosome profiling at isoform level reveals evolutionary conserved impacts of differential splicing on the proteome

Genes express multiple mRNA isoforms through alternative processing. Here the authors analyze ribosome profiling data with ORQAS (ORF quantification pipeline for alternative splicing) and report that 40–50% of the expressed mRNA isoforms are translated.

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Detalles Bibliográficos
Autores principales: Marina Reixachs-Solé, Jorge Ruiz-Orera, M. Mar Albà, Eduardo Eyras
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Science
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Acceso en línea:https://doaj.org/article/8300914fcd7944f19456d74ca9806c68
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