Integrating structure to protein-protein interaction networks that drive metastasis to brain and lung in breast cancer.

Blocking specific protein interactions can lead to human diseases. Accordingly, protein interactions and the structural knowledge on interacting surfaces of proteins (interfaces) have an important role in predicting the genotype-phenotype relationship. We have built the phenotype specific sub-networ...

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Autores principales: H Billur Engin, Emre Guney, Ozlem Keskin, Baldo Oliva, Attila Gursoy
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/830506bb3c5b454fb76d3a60cd73bd18
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