Empowering clinical research in a decentralized world

The COVID-19 pandemic has been a catalyst for the implementation of decentralized clinical trials (DCTs) enabled by digital health technologies (DHTs) in the field while curtailing in-person interactions and putting significant demands on health care resources. DHTs offer improvements in real-time d...

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Autores principales:	Walter De Brouwer, Chirag J. Patel, Arjun K. Manrai, Isaac R. Rodriguez-Chavez, Nirav R. Shah
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Computer applications to medicine. Medical informatics R858-859.7
Acceso en línea:	https://doaj.org/article/830d626f55c64189ba35deb023e9b331
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spelling	oai:doaj.org-article:830d626f55c64189ba35deb023e9b3312021-12-02T18:18:42ZEmpowering clinical research in a decentralized world10.1038/s41746-021-00473-w2398-6352https://doaj.org/article/830d626f55c64189ba35deb023e9b3312021-07-01T00:00:00Zhttps://doi.org/10.1038/s41746-021-00473-whttps://doaj.org/toc/2398-6352The COVID-19 pandemic has been a catalyst for the implementation of decentralized clinical trials (DCTs) enabled by digital health technologies (DHTs) in the field while curtailing in-person interactions and putting significant demands on health care resources. DHTs offer improvements in real-time data acquisition remotely while maintaining privacy and security. Here, we describe the implications of technologies, including edge computing, zero-trust environments, and federated computing in DCTs enabled by DHTs. Taken together, these technologies—in the setting of policy and regulation that enable their use while protecting the users—extend the scope and accelerate the pace of clinical research.Walter De BrouwerChirag J. PatelArjun K. ManraiIsaac R. Rodriguez-ChavezNirav R. ShahNature PortfolioarticleComputer applications to medicine. Medical informaticsR858-859.7ENnpj Digital Medicine, Vol 4, Iss 1, Pp 1-5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Computer applications to medicine. Medical informatics R858-859.7
spellingShingle	Computer applications to medicine. Medical informatics R858-859.7 Walter De Brouwer Chirag J. Patel Arjun K. Manrai Isaac R. Rodriguez-Chavez Nirav R. Shah Empowering clinical research in a decentralized world
description	The COVID-19 pandemic has been a catalyst for the implementation of decentralized clinical trials (DCTs) enabled by digital health technologies (DHTs) in the field while curtailing in-person interactions and putting significant demands on health care resources. DHTs offer improvements in real-time data acquisition remotely while maintaining privacy and security. Here, we describe the implications of technologies, including edge computing, zero-trust environments, and federated computing in DCTs enabled by DHTs. Taken together, these technologies—in the setting of policy and regulation that enable their use while protecting the users—extend the scope and accelerate the pace of clinical research.
format	article
author	Walter De Brouwer Chirag J. Patel Arjun K. Manrai Isaac R. Rodriguez-Chavez Nirav R. Shah
author_facet	Walter De Brouwer Chirag J. Patel Arjun K. Manrai Isaac R. Rodriguez-Chavez Nirav R. Shah
author_sort	Walter De Brouwer
title	Empowering clinical research in a decentralized world
title_short	Empowering clinical research in a decentralized world
title_full	Empowering clinical research in a decentralized world
title_fullStr	Empowering clinical research in a decentralized world
title_full_unstemmed	Empowering clinical research in a decentralized world
title_sort	empowering clinical research in a decentralized world
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/830d626f55c64189ba35deb023e9b331
work_keys_str_mv	AT walterdebrouwer empoweringclinicalresearchinadecentralizedworld AT chiragjpatel empoweringclinicalresearchinadecentralizedworld AT arjunkmanrai empoweringclinicalresearchinadecentralizedworld AT isaacrrodriguezchavez empoweringclinicalresearchinadecentralizedworld AT niravrshah empoweringclinicalresearchinadecentralizedworld
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Empowering clinical research in a decentralized world

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