Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer

Single cell RNA sequencing is a powerful tool for understanding cellular diversity but is limited by cost, throughput and sample preparation. Here the authors use nanogrid technology with integrated imaging to sequence thousands of cancer nuclei in parallel from fresh or frozen tissue.

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Autores principales:	Ruli Gao, Charissa Kim, Emi Sei, Theodoros Foukakis, Nicola Crosetto, Leong-Keat Chan, Maithreyan Srinivasan, Hong Zhang, Funda Meric-Bernstam, Nicholas Navin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/830f1e7e517147f0b71c9f627efb4d1b
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spelling	oai:doaj.org-article:830f1e7e517147f0b71c9f627efb4d1b2021-12-02T10:48:28ZNanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer10.1038/s41467-017-00244-w2041-1723https://doaj.org/article/830f1e7e517147f0b71c9f627efb4d1b2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00244-whttps://doaj.org/toc/2041-1723Single cell RNA sequencing is a powerful tool for understanding cellular diversity but is limited by cost, throughput and sample preparation. Here the authors use nanogrid technology with integrated imaging to sequence thousands of cancer nuclei in parallel from fresh or frozen tissue.Ruli GaoCharissa KimEmi SeiTheodoros FoukakisNicola CrosettoLeong-Keat ChanMaithreyan SrinivasanHong ZhangFunda Meric-BernstamNicholas NavinNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ruli Gao Charissa Kim Emi Sei Theodoros Foukakis Nicola Crosetto Leong-Keat Chan Maithreyan Srinivasan Hong Zhang Funda Meric-Bernstam Nicholas Navin Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer
description	Single cell RNA sequencing is a powerful tool for understanding cellular diversity but is limited by cost, throughput and sample preparation. Here the authors use nanogrid technology with integrated imaging to sequence thousands of cancer nuclei in parallel from fresh or frozen tissue.
format	article
author	Ruli Gao Charissa Kim Emi Sei Theodoros Foukakis Nicola Crosetto Leong-Keat Chan Maithreyan Srinivasan Hong Zhang Funda Meric-Bernstam Nicholas Navin
author_facet	Ruli Gao Charissa Kim Emi Sei Theodoros Foukakis Nicola Crosetto Leong-Keat Chan Maithreyan Srinivasan Hong Zhang Funda Meric-Bernstam Nicholas Navin
author_sort	Ruli Gao
title	Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer
title_short	Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer
title_full	Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer
title_fullStr	Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer
title_full_unstemmed	Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer
title_sort	nanogrid single-nucleus rna sequencing reveals phenotypic diversity in breast cancer
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/830f1e7e517147f0b71c9f627efb4d1b
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Nanogrid single-nucleus RNA sequencing reveals phenotypic diversity in breast cancer

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