Noradrenergic symptom cluster in depression

Stuart Montgomery1, Mike Briley21Imperial College School of Medicine, London, UK; 2NeuroBiz Consulting and Communication, Castres, FranceDepression is characterized by a wide range of diverse symptoms, the severity of which can be quantified by various depression rating scales, such as the Montgomer...

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Autores principales:	Montgomery S, Briley M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/8313ed4dd7b24e1c84fb9ab0cbd72a25
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spelling	oai:doaj.org-article:8313ed4dd7b24e1c84fb9ab0cbd72a252021-12-02T07:52:19ZNoradrenergic symptom cluster in depression1176-63281178-2021https://doaj.org/article/8313ed4dd7b24e1c84fb9ab0cbd72a252011-05-01T00:00:00Zhttp://www.dovepress.com/noradrenergic-symptom-cluster-in-depression-a7565https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Stuart Montgomery1, Mike Briley21Imperial College School of Medicine, London, UK; 2NeuroBiz Consulting and Communication, Castres, FranceDepression is characterized by a wide range of diverse symptoms, the severity of which can be quantified by various depression rating scales, such as the Montgomery Asberg Depression Rating Scale. Analyses of the individual items of this scale in patients treated with the selective serotonin reuptake inhibitors (SSRIs) have shown that not all items respond equally or with the same time of onset of improvement (Table 1).1,2 The items which respond less well or more slowly with SSRIs include lassitude, loss of energy, retardation of thoughts or actions, as well as concentration difficulties and loss of alertness. The loss of interest or pleasure that depressed patients experience (anhedonia) also responds poorly to SSRIs, and patients often complain of emotional indifference or blunting. Certain sleep difficulties are sometimes worsened by SSRIs. Appetite loss can be aggravated by certain SSRIs, an effect which can be made worse by nausea at the beginning of treatment.Montgomery SBriley MDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2011, Iss Supplement 1, Pp 1-2 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Montgomery S Briley M Noradrenergic symptom cluster in depression
description	Stuart Montgomery1, Mike Briley21Imperial College School of Medicine, London, UK; 2NeuroBiz Consulting and Communication, Castres, FranceDepression is characterized by a wide range of diverse symptoms, the severity of which can be quantified by various depression rating scales, such as the Montgomery Asberg Depression Rating Scale. Analyses of the individual items of this scale in patients treated with the selective serotonin reuptake inhibitors (SSRIs) have shown that not all items respond equally or with the same time of onset of improvement (Table 1).1,2 The items which respond less well or more slowly with SSRIs include lassitude, loss of energy, retardation of thoughts or actions, as well as concentration difficulties and loss of alertness. The loss of interest or pleasure that depressed patients experience (anhedonia) also responds poorly to SSRIs, and patients often complain of emotional indifference or blunting. Certain sleep difficulties are sometimes worsened by SSRIs. Appetite loss can be aggravated by certain SSRIs, an effect which can be made worse by nausea at the beginning of treatment.
format	article
author	Montgomery S Briley M
author_facet	Montgomery S Briley M
author_sort	Montgomery S
title	Noradrenergic symptom cluster in depression
title_short	Noradrenergic symptom cluster in depression
title_full	Noradrenergic symptom cluster in depression
title_fullStr	Noradrenergic symptom cluster in depression
title_full_unstemmed	Noradrenergic symptom cluster in depression
title_sort	noradrenergic symptom cluster in depression
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/8313ed4dd7b24e1c84fb9ab0cbd72a25
work_keys_str_mv	AT montgomerys noradrenergicsymptomclusterindepression AT brileym noradrenergicsymptomclusterindepression
_version_	1718399111325024256

Noradrenergic symptom cluster in depression

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