APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection

An et al. determine the presence of variants of the innate immune factor APOL1 in four cohorts of HIV-positive patients. The study suggests that APOL1 might confer carriers of two variant alleles protection from HIV related opportunistic infections, especially fungal infections.

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Autores principales:	Ping An, Efe Sezgin, Gregory D. Kirk, Priya Duggal, Elizabeth Binns-Roemer, George Nelson, Sophie Limou, Mark L. Van Natta, Douglas A. Jabs, Michelle Estrella, Jeffrey B. Kopp, Cheryl A. Winkler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/831bd8c038714b82bb61a55cbf435f8a
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spelling	oai:doaj.org-article:831bd8c038714b82bb61a55cbf435f8a2021-12-02T13:34:50ZAPOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection10.1038/s42003-021-01812-z2399-3642https://doaj.org/article/831bd8c038714b82bb61a55cbf435f8a2021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01812-zhttps://doaj.org/toc/2399-3642An et al. determine the presence of variants of the innate immune factor APOL1 in four cohorts of HIV-positive patients. The study suggests that APOL1 might confer carriers of two variant alleles protection from HIV related opportunistic infections, especially fungal infections.Ping AnEfe SezginGregory D. KirkPriya DuggalElizabeth Binns-RoemerGeorge NelsonSophie LimouMark L. Van NattaDouglas A. JabsMichelle EstrellaJeffrey B. KoppCheryl A. WinklerNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Ping An Efe Sezgin Gregory D. Kirk Priya Duggal Elizabeth Binns-Roemer George Nelson Sophie Limou Mark L. Van Natta Douglas A. Jabs Michelle Estrella Jeffrey B. Kopp Cheryl A. Winkler APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection
description	An et al. determine the presence of variants of the innate immune factor APOL1 in four cohorts of HIV-positive patients. The study suggests that APOL1 might confer carriers of two variant alleles protection from HIV related opportunistic infections, especially fungal infections.
format	article
author	Ping An Efe Sezgin Gregory D. Kirk Priya Duggal Elizabeth Binns-Roemer George Nelson Sophie Limou Mark L. Van Natta Douglas A. Jabs Michelle Estrella Jeffrey B. Kopp Cheryl A. Winkler
author_facet	Ping An Efe Sezgin Gregory D. Kirk Priya Duggal Elizabeth Binns-Roemer George Nelson Sophie Limou Mark L. Van Natta Douglas A. Jabs Michelle Estrella Jeffrey B. Kopp Cheryl A. Winkler
author_sort	Ping An
title	APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection
title_short	APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection
title_full	APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection
title_fullStr	APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection
title_full_unstemmed	APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection
title_sort	apol1 variant alleles associate with reduced risk for opportunistic infections in hiv infection
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/831bd8c038714b82bb61a55cbf435f8a
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APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection

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