Synthesis of Graphite Paste/Molecularly Imprinted Polymer (MIP) Electrodes Based on Polyeugenol as a Glucose Sensor with Potentiometric Method

Diabetes mellitus is a chronic disease in which the body is unable to metabolize carbohydrates, fats, and proteins. In this study, eugenol was polymerized and then contacted with glucose and crosslinked using polyethylene glycol diglycidyl ether (PEGDE). The resulted PE-Glucose-PEGDE was eluted usin...

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Autores principales:	Muhammad Cholid Djunaidi, Mei Dian Risda Afriani, Gunawan Gunawan, Miratul Khasanah
Formato:	article
Lenguaje:	EN
Publicado:	Department of Chemistry, Universitas Gadjah Mada 2021
Materias:	polyeugenol imprinted polymer electrode glucose potentiometry Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/831be1872561462bb80a290725c6bfac
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spelling	oai:doaj.org-article:831be1872561462bb80a290725c6bfac2021-12-02T17:09:37ZSynthesis of Graphite Paste/Molecularly Imprinted Polymer (MIP) Electrodes Based on Polyeugenol as a Glucose Sensor with Potentiometric Method1411-94202460-157810.22146/ijc.58964https://doaj.org/article/831be1872561462bb80a290725c6bfac2021-05-01T00:00:00Zhttps://jurnal.ugm.ac.id/ijc/article/view/58964https://doaj.org/toc/1411-9420https://doaj.org/toc/2460-1578Diabetes mellitus is a chronic disease in which the body is unable to metabolize carbohydrates, fats, and proteins. In this study, eugenol was polymerized and then contacted with glucose and crosslinked using polyethylene glycol diglycidyl ether (PEGDE). The resulted PE-Glucose-PEGDE was eluted using ethanol to form MIP-Glucose. It was then characterized by FTIR, SEM, electrodes using the Eutech 510 potentiostat and UV-Vis spectrophotometer. The result of polyeugenol synthesis is a reddish-brown powder with a yield of 99.90% and a molecular weight of 6318.033 g/mol. UV-Vis spectrophotometer analysis showed that the contacted glucose was 2152.505 ppm. SEM results showed differences in the surface morphology of the material, indicating the formation of cavities in MIP and ESM, while no cavities are found in NIP and ESN. The electrode optimization resulted in the best composition ratio of MIP 1 mol: paraffin: graphite, respectively of 20:35:45. The resulting electrode has a Nernst factor of 20.24 mV/decade with a measurement range of 10–5–10–1 M, a limit of detection value of 8.363 × 10–5 M, and the value of the selectivity coefficient (Kij) of the electrodes in a (10–5–10–1) M fructose solution was 0.3733; 0.23048; 0.17864; 0.12359; 0.1073.Muhammad Cholid DjunaidiMei Dian Risda AfrianiGunawan GunawanMiratul KhasanahDepartment of Chemistry, Universitas Gadjah Madaarticlepolyeugenolimprinted polymerelectrodeglucosepotentiometryChemistryQD1-999ENIndonesian Journal of Chemistry, Vol 21, Iss 4, Pp 816-824 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	polyeugenol imprinted polymer electrode glucose potentiometry Chemistry QD1-999
spellingShingle	polyeugenol imprinted polymer electrode glucose potentiometry Chemistry QD1-999 Muhammad Cholid Djunaidi Mei Dian Risda Afriani Gunawan Gunawan Miratul Khasanah Synthesis of Graphite Paste/Molecularly Imprinted Polymer (MIP) Electrodes Based on Polyeugenol as a Glucose Sensor with Potentiometric Method
description	Diabetes mellitus is a chronic disease in which the body is unable to metabolize carbohydrates, fats, and proteins. In this study, eugenol was polymerized and then contacted with glucose and crosslinked using polyethylene glycol diglycidyl ether (PEGDE). The resulted PE-Glucose-PEGDE was eluted using ethanol to form MIP-Glucose. It was then characterized by FTIR, SEM, electrodes using the Eutech 510 potentiostat and UV-Vis spectrophotometer. The result of polyeugenol synthesis is a reddish-brown powder with a yield of 99.90% and a molecular weight of 6318.033 g/mol. UV-Vis spectrophotometer analysis showed that the contacted glucose was 2152.505 ppm. SEM results showed differences in the surface morphology of the material, indicating the formation of cavities in MIP and ESM, while no cavities are found in NIP and ESN. The electrode optimization resulted in the best composition ratio of MIP 1 mol: paraffin: graphite, respectively of 20:35:45. The resulting electrode has a Nernst factor of 20.24 mV/decade with a measurement range of 10–5–10–1 M, a limit of detection value of 8.363 × 10–5 M, and the value of the selectivity coefficient (Kij) of the electrodes in a (10–5–10–1) M fructose solution was 0.3733; 0.23048; 0.17864; 0.12359; 0.1073.
format	article
author	Muhammad Cholid Djunaidi Mei Dian Risda Afriani Gunawan Gunawan Miratul Khasanah
author_facet	Muhammad Cholid Djunaidi Mei Dian Risda Afriani Gunawan Gunawan Miratul Khasanah
author_sort	Muhammad Cholid Djunaidi
title	Synthesis of Graphite Paste/Molecularly Imprinted Polymer (MIP) Electrodes Based on Polyeugenol as a Glucose Sensor with Potentiometric Method
title_short	Synthesis of Graphite Paste/Molecularly Imprinted Polymer (MIP) Electrodes Based on Polyeugenol as a Glucose Sensor with Potentiometric Method
title_full	Synthesis of Graphite Paste/Molecularly Imprinted Polymer (MIP) Electrodes Based on Polyeugenol as a Glucose Sensor with Potentiometric Method
title_fullStr	Synthesis of Graphite Paste/Molecularly Imprinted Polymer (MIP) Electrodes Based on Polyeugenol as a Glucose Sensor with Potentiometric Method
title_full_unstemmed	Synthesis of Graphite Paste/Molecularly Imprinted Polymer (MIP) Electrodes Based on Polyeugenol as a Glucose Sensor with Potentiometric Method
title_sort	synthesis of graphite paste/molecularly imprinted polymer (mip) electrodes based on polyeugenol as a glucose sensor with potentiometric method
publisher	Department of Chemistry, Universitas Gadjah Mada
publishDate	2021
url	https://doaj.org/article/831be1872561462bb80a290725c6bfac
work_keys_str_mv	AT muhammadcholiddjunaidi synthesisofgraphitepastemolecularlyimprintedpolymermipelectrodesbasedonpolyeugenolasaglucosesensorwithpotentiometricmethod AT meidianrisdaafriani synthesisofgraphitepastemolecularlyimprintedpolymermipelectrodesbasedonpolyeugenolasaglucosesensorwithpotentiometricmethod AT gunawangunawan synthesisofgraphitepastemolecularlyimprintedpolymermipelectrodesbasedonpolyeugenolasaglucosesensorwithpotentiometricmethod AT miratulkhasanah synthesisofgraphitepastemolecularlyimprintedpolymermipelectrodesbasedonpolyeugenolasaglucosesensorwithpotentiometricmethod
_version_	1718381508829380608

Synthesis of Graphite Paste/Molecularly Imprinted Polymer (MIP) Electrodes Based on Polyeugenol as a Glucose Sensor with Potentiometric Method

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