Functional Identification of Complement Factor D and Analysis of Its Expression during GCRV Infection in Grass Carp (<i>Ctenopharyngodon</i> <i>idella</i>)

Complement factor D (Df) is a serine protease well known for activating the alternative pathway (AP) in mammals by promoting the cleavage of complement component 3 (C3), thus becoming involved in innate defense. In teleost fish, however, the functional mechanisms of Df in the AP and against pathogen...

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Bibliographic Details
Main Authors: Chunhua Ding, Tiaoyi Xiao, Beibei Qin, Baohong Xu, Zhao Lv, Hongquan Wang
Format: article
Language:EN
Published: MDPI AG 2021
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Online Access:https://doaj.org/article/8325d381c9dd45eeaf7dc6efa60e147d
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