Functional Identification of Complement Factor D and Analysis of Its Expression during GCRV Infection in Grass Carp (<i>Ctenopharyngodon</i> <i>idella</i>)
Complement factor D (Df) is a serine protease well known for activating the alternative pathway (AP) in mammals by promoting the cleavage of complement component 3 (C3), thus becoming involved in innate defense. In teleost fish, however, the functional mechanisms of Df in the AP and against pathogen...
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Main Authors: | , , , , , |
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Format: | article |
Language: | EN |
Published: |
MDPI AG
2021
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Subjects: | |
Online Access: | https://doaj.org/article/8325d381c9dd45eeaf7dc6efa60e147d |
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