Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI

Patients with ST-elevation MI (STEMI) usually have a huge thrombus burden in the infarct-related artery. Stenting may lead to high chances of the slow-flow/no-reflow phenomenon that leads to periprocedural MI and adverse cardiovascular events. Deferred stenting may be beneficial in this situation as...

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Autores principales: Akshyaya Pradhan, Monika Bhandari, Pravesh Vishwakarma, Rishi Sethi
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Lenguaje:EN
Publicado: Radcliffe Medical Media 2021
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Acceso en línea:https://doaj.org/article/833dfe9d71d24cb88434992f95c3e93a
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spelling oai:doaj.org-article:833dfe9d71d24cb88434992f95c3e93a2021-12-04T16:04:08ZDeferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI10.15420/ecr.2020.311758-37641758-3756https://doaj.org/article/833dfe9d71d24cb88434992f95c3e93a2021-03-01T00:00:00Zhttps://www.ecrjournal.com/articleindex/ecr.2020.31https://doaj.org/toc/1758-3756https://doaj.org/toc/1758-3764Patients with ST-elevation MI (STEMI) usually have a huge thrombus burden in the infarct-related artery. Stenting may lead to high chances of the slow-flow/no-reflow phenomenon that leads to periprocedural MI and adverse cardiovascular events. Deferred stenting may be beneficial in this situation as the thrombus burden will reduce, mitigating the slow-flow/no-reflow phenomenon. However, routine deferral of stenting in patients with STEMI has not been found to be beneficial, but when the patient is properly selected, deferred stenting has the potential for reducing the final infarct size. The authors report the safety and feasibility of deferred stenting after 5 days of prolonged anticoagulation in a 45-year-old smoker with STEMI who had a large thrombus load shown on an angiogram. They review the registries, trials and meta-analyses on deferred stenting in the literature and analyse the benefits and harms of the strategy. They also propose an algorithm for applying a strategy for deferred stenting in clinical practice based on the available data.Akshyaya PradhanMonika BhandariPravesh VishwakarmaRishi SethiRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENEuropean Cardiology Review , Vol 16, Iss , Pp - (2021)
institution DOAJ
collection DOAJ
language EN
topic Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Diseases of the circulatory (Cardiovascular) system
RC666-701
Akshyaya Pradhan
Monika Bhandari
Pravesh Vishwakarma
Rishi Sethi
Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI
description Patients with ST-elevation MI (STEMI) usually have a huge thrombus burden in the infarct-related artery. Stenting may lead to high chances of the slow-flow/no-reflow phenomenon that leads to periprocedural MI and adverse cardiovascular events. Deferred stenting may be beneficial in this situation as the thrombus burden will reduce, mitigating the slow-flow/no-reflow phenomenon. However, routine deferral of stenting in patients with STEMI has not been found to be beneficial, but when the patient is properly selected, deferred stenting has the potential for reducing the final infarct size. The authors report the safety and feasibility of deferred stenting after 5 days of prolonged anticoagulation in a 45-year-old smoker with STEMI who had a large thrombus load shown on an angiogram. They review the registries, trials and meta-analyses on deferred stenting in the literature and analyse the benefits and harms of the strategy. They also propose an algorithm for applying a strategy for deferred stenting in clinical practice based on the available data.
format article
author Akshyaya Pradhan
Monika Bhandari
Pravesh Vishwakarma
Rishi Sethi
author_facet Akshyaya Pradhan
Monika Bhandari
Pravesh Vishwakarma
Rishi Sethi
author_sort Akshyaya Pradhan
title Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI
title_short Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI
title_full Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI
title_fullStr Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI
title_full_unstemmed Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI
title_sort deferred stenting for heavy thrombus burden during percutaneous coronary intervention for st-elevation mi
publisher Radcliffe Medical Media
publishDate 2021
url https://doaj.org/article/833dfe9d71d24cb88434992f95c3e93a
work_keys_str_mv AT akshyayapradhan deferredstentingforheavythrombusburdenduringpercutaneouscoronaryinterventionforstelevationmi
AT monikabhandari deferredstentingforheavythrombusburdenduringpercutaneouscoronaryinterventionforstelevationmi
AT praveshvishwakarma deferredstentingforheavythrombusburdenduringpercutaneouscoronaryinterventionforstelevationmi
AT rishisethi deferredstentingforheavythrombusburdenduringpercutaneouscoronaryinterventionforstelevationmi
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