Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease

Abstract The mammalian heart contains heterogeneous cell types contributing to pathological changes in cardiac disease. In this Comment, we explore how single-cell transcriptomic approaches are unveiling intricate cellular mechanisms and gene co-expression networks that regulate the workings, and fa...

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Autores principales:	Matthew Ackers-Johnson, Wilson Lek Wen Tan, Roger Sik-Yin Foo
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/833f1df0df2b40b89d72a69510aa79ec
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spelling	oai:doaj.org-article:833f1df0df2b40b89d72a69510aa79ec2021-12-02T14:39:09ZFollowing hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease10.1038/s41467-018-06894-82041-1723https://doaj.org/article/833f1df0df2b40b89d72a69510aa79ec2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06894-8https://doaj.org/toc/2041-1723Abstract The mammalian heart contains heterogeneous cell types contributing to pathological changes in cardiac disease. In this Comment, we explore how single-cell transcriptomic approaches are unveiling intricate cellular mechanisms and gene co-expression networks that regulate the workings, and failings, of the heart.Matthew Ackers-JohnsonWilson Lek Wen TanRoger Sik-Yin FooNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-4 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Matthew Ackers-Johnson Wilson Lek Wen Tan Roger Sik-Yin Foo Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease
description	Abstract The mammalian heart contains heterogeneous cell types contributing to pathological changes in cardiac disease. In this Comment, we explore how single-cell transcriptomic approaches are unveiling intricate cellular mechanisms and gene co-expression networks that regulate the workings, and failings, of the heart.
format	article
author	Matthew Ackers-Johnson Wilson Lek Wen Tan Roger Sik-Yin Foo
author_facet	Matthew Ackers-Johnson Wilson Lek Wen Tan Roger Sik-Yin Foo
author_sort	Matthew Ackers-Johnson
title	Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease
title_short	Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease
title_full	Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease
title_fullStr	Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease
title_full_unstemmed	Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease
title_sort	following hearts, one cell at a time: recent applications of single-cell rna sequencing to the understanding of heart disease
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/833f1df0df2b40b89d72a69510aa79ec
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Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease

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