Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity

Current databases of V genes for antibody repertoire have limitations. Here Corcoran et al. develop a computational approach named IgDiscover that can identify germline V gene sequences from expressed antibody repertoires to high specificity and completeness.

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Autores principales:	Martin M. Corcoran, Ganesh E. Phad, Néstor Vázquez Bernat, Christiane Stahl-Hennig, Noriyuki Sumida, Mats A.A. Persson, Marcel Martin, Gunilla B. Karlsson Hedestam
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8347676fcb7f429d81b27ddb94c2bdb4
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spelling	oai:doaj.org-article:8347676fcb7f429d81b27ddb94c2bdb42021-12-02T15:33:48ZProduction of individualized V gene databases reveals high levels of immunoglobulin genetic diversity10.1038/ncomms136422041-1723https://doaj.org/article/8347676fcb7f429d81b27ddb94c2bdb42016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13642https://doaj.org/toc/2041-1723Current databases of V genes for antibody repertoire have limitations. Here Corcoran et al. develop a computational approach named IgDiscover that can identify germline V gene sequences from expressed antibody repertoires to high specificity and completeness.Martin M. CorcoranGanesh E. PhadNéstor Vázquez BernatChristiane Stahl-HennigNoriyuki SumidaMats A.A. PerssonMarcel MartinGunilla B. Karlsson HedestamNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Martin M. Corcoran Ganesh E. Phad Néstor Vázquez Bernat Christiane Stahl-Hennig Noriyuki Sumida Mats A.A. Persson Marcel Martin Gunilla B. Karlsson Hedestam Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity
description	Current databases of V genes for antibody repertoire have limitations. Here Corcoran et al. develop a computational approach named IgDiscover that can identify germline V gene sequences from expressed antibody repertoires to high specificity and completeness.
format	article
author	Martin M. Corcoran Ganesh E. Phad Néstor Vázquez Bernat Christiane Stahl-Hennig Noriyuki Sumida Mats A.A. Persson Marcel Martin Gunilla B. Karlsson Hedestam
author_facet	Martin M. Corcoran Ganesh E. Phad Néstor Vázquez Bernat Christiane Stahl-Hennig Noriyuki Sumida Mats A.A. Persson Marcel Martin Gunilla B. Karlsson Hedestam
author_sort	Martin M. Corcoran
title	Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity
title_short	Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity
title_full	Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity
title_fullStr	Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity
title_full_unstemmed	Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity
title_sort	production of individualized v gene databases reveals high levels of immunoglobulin genetic diversity
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/8347676fcb7f429d81b27ddb94c2bdb4
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Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity

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