Effectiveness of Exercise Therapy on Gait Function in Diabetic Peripheral Neuropathy Patients: A Systematic Review of Randomized Controlled Trials

Haimanot Melese, Abayneh Alamer, Melaku Hailu Temesgen, Gebresilassie Kahsay Department of Physiotherapy, School of Medicine, College of Health Sciences and Ayder Comprehensive Specialized Hospital, Mekelle University, Mekelle, EthiopiaCorrespondence: Haimanot Melese Tel +2510927608383Fax +251034441...

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Autores principales:	Melese H, Alamer A, Hailu Temesgen M, Kahsay G
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	exercise therapy diabetic pain functional training gait peripheral neuropathy systematic review Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/8362980cdbc54c58b6cba3fd2527a48d
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spelling	oai:doaj.org-article:8362980cdbc54c58b6cba3fd2527a48d2021-12-02T10:24:55ZEffectiveness of Exercise Therapy on Gait Function in Diabetic Peripheral Neuropathy Patients: A Systematic Review of Randomized Controlled Trials1178-7007https://doaj.org/article/8362980cdbc54c58b6cba3fd2527a48d2020-08-01T00:00:00Zhttps://www.dovepress.com/effectiveness-of-exercise-therapy-on-gait-function-in-diabetic-periphe-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Haimanot Melese, Abayneh Alamer, Melaku Hailu Temesgen, Gebresilassie Kahsay Department of Physiotherapy, School of Medicine, College of Health Sciences and Ayder Comprehensive Specialized Hospital, Mekelle University, Mekelle, EthiopiaCorrespondence: Haimanot Melese Tel +2510927608383Fax +2510344416681/91Email haimanotphysio@gmail.comAbstract: The purpose of this study was to review the current evidence on the effectiveness of exercise therapy on gait function in patients with diabetic peripheral neuropathy. A comprehensive search of literature published between October 2010 and May 2020 was conducted using the following electronic databases; PubMed, AMED, CINAHL, ScienceDirect, Cochrane Library, PEDro and Google Scholar. Randomized control trials conducted to determine the effectiveness of exercise therapy on gait function in patients with diabetic neuropathy were included in this review. Non-English language published papers were excluded. This review was done in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Data extraction and risk of bias assessment of the studies were carried out independently by two authors. The methodological quality of the studies was evaluated using the PEDro scale and GRADE approach. The overall methodological quality of studies rated from moderate to high. Meta-analysis was not carried out due to the heterogeneity of included trials. The primary outcome measures of gait functions were the six-minute walk test, 10-meter walk test and Tinetti scale. Nine randomized controlled trials with 370 participants were analyzed. Out of them, eight studies proved its effectiveness on gait function on individuals with diabetic peripheral neuropathy. The finding of this study suggested that multi-component exercise therapy consisted of strength, ROM exercise, balance, flexibility and stretching exercises, circuit exercise training, and gait training found to enhance gait function for individuals suffering with diabetic peripheral neuropathy compared to control groups.Keywords: exercise therapy, diabetic pain, functional training, gait, peripheral neuropathy, systematic reviewMelese HAlamer AHailu Temesgen MKahsay GDove Medical Pressarticleexercise therapydiabetic painfunctional traininggaitperipheral neuropathysystematic reviewSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 13, Pp 2753-2764 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	exercise therapy diabetic pain functional training gait peripheral neuropathy systematic review Specialties of internal medicine RC581-951
spellingShingle	exercise therapy diabetic pain functional training gait peripheral neuropathy systematic review Specialties of internal medicine RC581-951 Melese H Alamer A Hailu Temesgen M Kahsay G Effectiveness of Exercise Therapy on Gait Function in Diabetic Peripheral Neuropathy Patients: A Systematic Review of Randomized Controlled Trials
description	Haimanot Melese, Abayneh Alamer, Melaku Hailu Temesgen, Gebresilassie Kahsay Department of Physiotherapy, School of Medicine, College of Health Sciences and Ayder Comprehensive Specialized Hospital, Mekelle University, Mekelle, EthiopiaCorrespondence: Haimanot Melese Tel +2510927608383Fax +2510344416681/91Email haimanotphysio@gmail.comAbstract: The purpose of this study was to review the current evidence on the effectiveness of exercise therapy on gait function in patients with diabetic peripheral neuropathy. A comprehensive search of literature published between October 2010 and May 2020 was conducted using the following electronic databases; PubMed, AMED, CINAHL, ScienceDirect, Cochrane Library, PEDro and Google Scholar. Randomized control trials conducted to determine the effectiveness of exercise therapy on gait function in patients with diabetic neuropathy were included in this review. Non-English language published papers were excluded. This review was done in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Data extraction and risk of bias assessment of the studies were carried out independently by two authors. The methodological quality of the studies was evaluated using the PEDro scale and GRADE approach. The overall methodological quality of studies rated from moderate to high. Meta-analysis was not carried out due to the heterogeneity of included trials. The primary outcome measures of gait functions were the six-minute walk test, 10-meter walk test and Tinetti scale. Nine randomized controlled trials with 370 participants were analyzed. Out of them, eight studies proved its effectiveness on gait function on individuals with diabetic peripheral neuropathy. The finding of this study suggested that multi-component exercise therapy consisted of strength, ROM exercise, balance, flexibility and stretching exercises, circuit exercise training, and gait training found to enhance gait function for individuals suffering with diabetic peripheral neuropathy compared to control groups.Keywords: exercise therapy, diabetic pain, functional training, gait, peripheral neuropathy, systematic review
format	article
author	Melese H Alamer A Hailu Temesgen M Kahsay G
author_facet	Melese H Alamer A Hailu Temesgen M Kahsay G
author_sort	Melese H
title	Effectiveness of Exercise Therapy on Gait Function in Diabetic Peripheral Neuropathy Patients: A Systematic Review of Randomized Controlled Trials
title_short	Effectiveness of Exercise Therapy on Gait Function in Diabetic Peripheral Neuropathy Patients: A Systematic Review of Randomized Controlled Trials
title_full	Effectiveness of Exercise Therapy on Gait Function in Diabetic Peripheral Neuropathy Patients: A Systematic Review of Randomized Controlled Trials
title_fullStr	Effectiveness of Exercise Therapy on Gait Function in Diabetic Peripheral Neuropathy Patients: A Systematic Review of Randomized Controlled Trials
title_full_unstemmed	Effectiveness of Exercise Therapy on Gait Function in Diabetic Peripheral Neuropathy Patients: A Systematic Review of Randomized Controlled Trials
title_sort	effectiveness of exercise therapy on gait function in diabetic peripheral neuropathy patients: a systematic review of randomized controlled trials
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/8362980cdbc54c58b6cba3fd2527a48d
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Effectiveness of Exercise Therapy on Gait Function in Diabetic Peripheral Neuropathy Patients: A Systematic Review of Randomized Controlled Trials

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