Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer

Inositol hexakisphosphate (IP6) is a known assembly cofactor for HIV-1. Here, the authors show the role of IP6 in the assembly of the Rous sarcoma virus (RSV). Reported cryo-ET structures of mature capsid-like particles (CLPs) suggest that IP6 modulates the formation of capsid polyhedrons of variabl...

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Autores principales:	Martin Obr, Clifton L. Ricana, Nadia Nikulin, Jon-Philip R. Feathers, Marco Klanschnig, Andreas Thader, Marc C. Johnson, Volker M. Vogt, Florian K. M. Schur, Robert A. Dick
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8367c143cb65471aa8e3f6f874525a62
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spelling	oai:doaj.org-article:8367c143cb65471aa8e3f6f874525a622021-12-02T14:47:29ZStructure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer10.1038/s41467-021-23506-02041-1723https://doaj.org/article/8367c143cb65471aa8e3f6f874525a622021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23506-0https://doaj.org/toc/2041-1723Inositol hexakisphosphate (IP6) is a known assembly cofactor for HIV-1. Here, the authors show the role of IP6 in the assembly of the Rous sarcoma virus (RSV). Reported cryo-ET structures of mature capsid-like particles (CLPs) suggest that IP6 modulates the formation of capsid polyhedrons of variable shape.Martin ObrClifton L. RicanaNadia NikulinJon-Philip R. FeathersMarco KlanschnigAndreas ThaderMarc C. JohnsonVolker M. VogtFlorian K. M. SchurRobert A. DickNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Martin Obr Clifton L. Ricana Nadia Nikulin Jon-Philip R. Feathers Marco Klanschnig Andreas Thader Marc C. Johnson Volker M. Vogt Florian K. M. Schur Robert A. Dick Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer
description	Inositol hexakisphosphate (IP6) is a known assembly cofactor for HIV-1. Here, the authors show the role of IP6 in the assembly of the Rous sarcoma virus (RSV). Reported cryo-ET structures of mature capsid-like particles (CLPs) suggest that IP6 modulates the formation of capsid polyhedrons of variable shape.
format	article
author	Martin Obr Clifton L. Ricana Nadia Nikulin Jon-Philip R. Feathers Marco Klanschnig Andreas Thader Marc C. Johnson Volker M. Vogt Florian K. M. Schur Robert A. Dick
author_facet	Martin Obr Clifton L. Ricana Nadia Nikulin Jon-Philip R. Feathers Marco Klanschnig Andreas Thader Marc C. Johnson Volker M. Vogt Florian K. M. Schur Robert A. Dick
author_sort	Martin Obr
title	Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer
title_short	Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer
title_full	Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer
title_fullStr	Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer
title_full_unstemmed	Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer
title_sort	structure of the mature rous sarcoma virus lattice reveals a role for ip6 in the formation of the capsid hexamer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8367c143cb65471aa8e3f6f874525a62
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Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer

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