Multifocal photodynamic therapy for diffuse choroidal hemangioma

Marcus Ang, Shu-Yen LeeSingapore Eye Research Institute, Singapore National Eye Centre, SingaporeBackground: A choroidal hemangioma is an uncommon benign vascular tumor of the choroid that can be either circumscribed or diffuse. In our experience, diffuse choroidal hemangiomas in Asian patients ofte...

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Autores principales: Ang M, Lee SY
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Publicado: Dove Medical Press 2012
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spelling oai:doaj.org-article:836c3a9a6f5b4fa786bd5615db5715172021-12-02T02:11:00ZMultifocal photodynamic therapy for diffuse choroidal hemangioma1177-54671177-5483https://doaj.org/article/836c3a9a6f5b4fa786bd5615db5715172012-09-01T00:00:00Zhttp://www.dovepress.com/multifocal-photodynamic-therapy-for-diffuse-choroidal-hemangioma-a10941https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Marcus Ang, Shu-Yen LeeSingapore Eye Research Institute, Singapore National Eye Centre, SingaporeBackground: A choroidal hemangioma is an uncommon benign vascular tumor of the choroid that can be either circumscribed or diffuse. In our experience, diffuse choroidal hemangiomas in Asian patients often require multiple photodynamic therapy (PDT) treatment sessions.Methods: We here provide a case report of a 7-year-old boy with Sturge–Weber syndrome who presented with diffuse choroidal hemangioma in the left eye. Five sessions of PDT treatment were required over a period of 1 year and a final optical coherence tomogram 3 months later revealed resolution of subretinal fluid and the choroidal hemangioma.Results: Final visual acuity was 20/100 in the left eye with resolution of subretinal fluid. This case report illustrates that a single application of PDT using standard published parameters was insufficient to achieve the destruction of the enlarged vessels. This experience is similar to previous Chinese reports on circumscribed choroidal hemangiomas. The decision for repeat treatment was based on subretinal fluid recurrence, rather than complete tumor regression.Conclusion: Our case report supports previous suggestions that larger dilated vessels in the vascular network of a choroidal hemangioma might affect the efficacy and selectivity of PDT in treating the eyes of Asian patients – which may explain the need for multiple treatments.Keywords: choroidal hemangioma, Sturge–Weber syndrome, optical coherence tomographyAng MLee SYDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 1467-1469 (2012)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Ang M
Lee SY
Multifocal photodynamic therapy for diffuse choroidal hemangioma
description Marcus Ang, Shu-Yen LeeSingapore Eye Research Institute, Singapore National Eye Centre, SingaporeBackground: A choroidal hemangioma is an uncommon benign vascular tumor of the choroid that can be either circumscribed or diffuse. In our experience, diffuse choroidal hemangiomas in Asian patients often require multiple photodynamic therapy (PDT) treatment sessions.Methods: We here provide a case report of a 7-year-old boy with Sturge–Weber syndrome who presented with diffuse choroidal hemangioma in the left eye. Five sessions of PDT treatment were required over a period of 1 year and a final optical coherence tomogram 3 months later revealed resolution of subretinal fluid and the choroidal hemangioma.Results: Final visual acuity was 20/100 in the left eye with resolution of subretinal fluid. This case report illustrates that a single application of PDT using standard published parameters was insufficient to achieve the destruction of the enlarged vessels. This experience is similar to previous Chinese reports on circumscribed choroidal hemangiomas. The decision for repeat treatment was based on subretinal fluid recurrence, rather than complete tumor regression.Conclusion: Our case report supports previous suggestions that larger dilated vessels in the vascular network of a choroidal hemangioma might affect the efficacy and selectivity of PDT in treating the eyes of Asian patients – which may explain the need for multiple treatments.Keywords: choroidal hemangioma, Sturge–Weber syndrome, optical coherence tomography
format article
author Ang M
Lee SY
author_facet Ang M
Lee SY
author_sort Ang M
title Multifocal photodynamic therapy for diffuse choroidal hemangioma
title_short Multifocal photodynamic therapy for diffuse choroidal hemangioma
title_full Multifocal photodynamic therapy for diffuse choroidal hemangioma
title_fullStr Multifocal photodynamic therapy for diffuse choroidal hemangioma
title_full_unstemmed Multifocal photodynamic therapy for diffuse choroidal hemangioma
title_sort multifocal photodynamic therapy for diffuse choroidal hemangioma
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/836c3a9a6f5b4fa786bd5615db571517
work_keys_str_mv AT angm multifocalphotodynamictherapyfordiffusechoroidalhemangioma
AT leesy multifocalphotodynamictherapyfordiffusechoroidalhemangioma
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