Network Walking charts transcriptional dynamics of nitrogen signaling by integrating validated and predicted genome-wide interactions

Temporal control of transcriptional networks enables organisms to adapt to changing environment. Here, the authors use a scaled-up cell-based assay to identify direct targets of nitrogen-early responsive transcription factors and validate a network path mediating dynamic nitrogen signaling in Arabid...

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Autores principales: Matthew D. Brooks, Jacopo Cirrone, Angelo V. Pasquino, Jose M. Alvarez, Joseph Swift, Shipra Mittal, Che-Lun Juang, Kranthi Varala, Rodrigo A. Gutiérrez, Gabriel Krouk, Dennis Shasha, Gloria M. Coruzzi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/8373c4440151476f9e29c51167aed1f3
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Sumario:Temporal control of transcriptional networks enables organisms to adapt to changing environment. Here, the authors use a scaled-up cell-based assay to identify direct targets of nitrogen-early responsive transcription factors and validate a network path mediating dynamic nitrogen signaling in Arabidopsis.