The Apelinergic System Immuno-Detection in the Abomasum and Duodenum of Sheep Grazing on Semi-Natural Pasture

Apelin (APLN) is an adipokine mainly produced by adipose tissue and related to an individual’s nutritional status as well as digestive apparatus functions. In this work, APLN and its receptor (APLNR) were investigated, by immunohistochemistry, in the abomasum and duodenum of 15 Comisana × Appenninic...

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Autores principales:	Elisa Palmioli, Cecilia Dall’Aglio, Michele Bellesi, Federico Maria Tardella, Sara Moscatelli, Paola Scocco, Francesca Mercati
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	apelin apelin receptor adipokines digestive system ovine immunohistochemistry Veterinary medicine SF600-1100 Zoology QL1-991
Acceso en línea:	https://doaj.org/article/837d4fa33e934e38ade8a3d113686d03
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spelling	oai:doaj.org-article:837d4fa33e934e38ade8a3d113686d032021-11-25T16:18:09ZThe Apelinergic System Immuno-Detection in the Abomasum and Duodenum of Sheep Grazing on Semi-Natural Pasture10.3390/ani111131732076-2615https://doaj.org/article/837d4fa33e934e38ade8a3d113686d032021-11-01T00:00:00Zhttps://www.mdpi.com/2076-2615/11/11/3173https://doaj.org/toc/2076-2615Apelin (APLN) is an adipokine mainly produced by adipose tissue and related to an individual’s nutritional status as well as digestive apparatus functions. In this work, APLN and its receptor (APLNR) were investigated, by immunohistochemistry, in the abomasum and duodenum of 15 Comisana × Appenninica adult sheep reared in a semi-natural pasture. Organ samples were collected after maximum pasture flowering (M × F group) and after maximum pasture dryness (M × D group); the experimental group (E × p group) received a feed supplementation of 600 grams/day/head of barley and corn in addition to M × D group feeding. APLN and APLNR were identified in the lining epithelium and the fundic gland chief cells of the abomasum. APLNR was observed in the lining epithelium, in the crypts and the serotonin secreting cells of the duodenum. Similar reactivity was observed between the M × F and E × p groups, while the M × D group showed a lower intensity of immunostaining for both APLN and APLNR in all positive structures but the duodenal serotonin neuroendocrine cells. Hence, our findings show that the E × p group presents a picture quite overlapped with M × F and suggest that food supplementation has a maintaining effect on the apelinergic system expression in the investigated digestive tracts of the sheep.Elisa PalmioliCecilia Dall’AglioMichele BellesiFederico Maria TardellaSara MoscatelliPaola ScoccoFrancesca MercatiMDPI AGarticleapelinapelin receptoradipokinesdigestive systemovineimmunohistochemistryVeterinary medicineSF600-1100ZoologyQL1-991ENAnimals, Vol 11, Iss 3173, p 3173 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	apelin apelin receptor adipokines digestive system ovine immunohistochemistry Veterinary medicine SF600-1100 Zoology QL1-991
spellingShingle	apelin apelin receptor adipokines digestive system ovine immunohistochemistry Veterinary medicine SF600-1100 Zoology QL1-991 Elisa Palmioli Cecilia Dall’Aglio Michele Bellesi Federico Maria Tardella Sara Moscatelli Paola Scocco Francesca Mercati The Apelinergic System Immuno-Detection in the Abomasum and Duodenum of Sheep Grazing on Semi-Natural Pasture
description	Apelin (APLN) is an adipokine mainly produced by adipose tissue and related to an individual’s nutritional status as well as digestive apparatus functions. In this work, APLN and its receptor (APLNR) were investigated, by immunohistochemistry, in the abomasum and duodenum of 15 Comisana × Appenninica adult sheep reared in a semi-natural pasture. Organ samples were collected after maximum pasture flowering (M × F group) and after maximum pasture dryness (M × D group); the experimental group (E × p group) received a feed supplementation of 600 grams/day/head of barley and corn in addition to M × D group feeding. APLN and APLNR were identified in the lining epithelium and the fundic gland chief cells of the abomasum. APLNR was observed in the lining epithelium, in the crypts and the serotonin secreting cells of the duodenum. Similar reactivity was observed between the M × F and E × p groups, while the M × D group showed a lower intensity of immunostaining for both APLN and APLNR in all positive structures but the duodenal serotonin neuroendocrine cells. Hence, our findings show that the E × p group presents a picture quite overlapped with M × F and suggest that food supplementation has a maintaining effect on the apelinergic system expression in the investigated digestive tracts of the sheep.
format	article
author	Elisa Palmioli Cecilia Dall’Aglio Michele Bellesi Federico Maria Tardella Sara Moscatelli Paola Scocco Francesca Mercati
author_facet	Elisa Palmioli Cecilia Dall’Aglio Michele Bellesi Federico Maria Tardella Sara Moscatelli Paola Scocco Francesca Mercati
author_sort	Elisa Palmioli
title	The Apelinergic System Immuno-Detection in the Abomasum and Duodenum of Sheep Grazing on Semi-Natural Pasture
title_short	The Apelinergic System Immuno-Detection in the Abomasum and Duodenum of Sheep Grazing on Semi-Natural Pasture
title_full	The Apelinergic System Immuno-Detection in the Abomasum and Duodenum of Sheep Grazing on Semi-Natural Pasture
title_fullStr	The Apelinergic System Immuno-Detection in the Abomasum and Duodenum of Sheep Grazing on Semi-Natural Pasture
title_full_unstemmed	The Apelinergic System Immuno-Detection in the Abomasum and Duodenum of Sheep Grazing on Semi-Natural Pasture
title_sort	apelinergic system immuno-detection in the abomasum and duodenum of sheep grazing on semi-natural pasture
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/837d4fa33e934e38ade8a3d113686d03
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The Apelinergic System Immuno-Detection in the Abomasum and Duodenum of Sheep Grazing on Semi-Natural Pasture

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