A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection

Animal models of group-B streptococcal infections are needed to develop effective therapies. Here, Andrade et al. present a mouse model in which the bacteria are transmitted from vaginally colonised pregnant females to their offspring, causing neonatal meningitis and neurological developmental disab...

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Autores principales: Elva Bonifácio Andrade, Ana Magalhães, Ana Puga, Madalena Costa, Joana Bravo, Camila Cabral Portugal, Adília Ribeiro, Margarida Correia-Neves, Augusto Faustino, Arnaud Firon, Patrick Trieu-Cuot, Teresa Summavielle, Paula Ferreira
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/8386576c08064b7cbf1996e40b3f601a
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spelling oai:doaj.org-article:8386576c08064b7cbf1996e40b3f601a2021-12-02T14:39:04ZA mouse model reproducing the pathophysiology of neonatal group B streptococcal infection10.1038/s41467-018-05492-y2041-1723https://doaj.org/article/8386576c08064b7cbf1996e40b3f601a2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05492-yhttps://doaj.org/toc/2041-1723Animal models of group-B streptococcal infections are needed to develop effective therapies. Here, Andrade et al. present a mouse model in which the bacteria are transmitted from vaginally colonised pregnant females to their offspring, causing neonatal meningitis and neurological developmental disabilities.Elva Bonifácio AndradeAna MagalhãesAna PugaMadalena CostaJoana BravoCamila Cabral PortugalAdília RibeiroMargarida Correia-NevesAugusto FaustinoArnaud FironPatrick Trieu-CuotTeresa SummaviellePaula FerreiraNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Elva Bonifácio Andrade
Ana Magalhães
Ana Puga
Madalena Costa
Joana Bravo
Camila Cabral Portugal
Adília Ribeiro
Margarida Correia-Neves
Augusto Faustino
Arnaud Firon
Patrick Trieu-Cuot
Teresa Summavielle
Paula Ferreira
A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection
description Animal models of group-B streptococcal infections are needed to develop effective therapies. Here, Andrade et al. present a mouse model in which the bacteria are transmitted from vaginally colonised pregnant females to their offspring, causing neonatal meningitis and neurological developmental disabilities.
format article
author Elva Bonifácio Andrade
Ana Magalhães
Ana Puga
Madalena Costa
Joana Bravo
Camila Cabral Portugal
Adília Ribeiro
Margarida Correia-Neves
Augusto Faustino
Arnaud Firon
Patrick Trieu-Cuot
Teresa Summavielle
Paula Ferreira
author_facet Elva Bonifácio Andrade
Ana Magalhães
Ana Puga
Madalena Costa
Joana Bravo
Camila Cabral Portugal
Adília Ribeiro
Margarida Correia-Neves
Augusto Faustino
Arnaud Firon
Patrick Trieu-Cuot
Teresa Summavielle
Paula Ferreira
author_sort Elva Bonifácio Andrade
title A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection
title_short A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection
title_full A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection
title_fullStr A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection
title_full_unstemmed A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection
title_sort mouse model reproducing the pathophysiology of neonatal group b streptococcal infection
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/8386576c08064b7cbf1996e40b3f601a
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