Laser Additively Manufactured Iron-Based Biocomposite: Microstructure, Degradation, and In Vitro Cell Behavior

A too slow degradation of iron (Fe) limits its orthopedic application. In this study, calcium chloride (CaCl2) was incorporated into a Fe-based biocomposite fabricated by laser additive manufacturing, with an aim to accelerate the degradation. It was found that CaCl2 with strong water absorptivity i...

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Autores principales:	Youwen Yang, Guoqing Cai, Mingli Yang, Dongsheng Wang, Shuping Peng, Zhigang Liu, Cijun Shuai
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	laser additive manufacturing iron bone implant calcium chloride degradation properties cell behavior Biotechnology TP248.13-248.65
Acceso en línea:	https://doaj.org/article/838edbfc8e164773823ab0a066100bc4
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spelling	oai:doaj.org-article:838edbfc8e164773823ab0a066100bc42021-12-02T10:56:36ZLaser Additively Manufactured Iron-Based Biocomposite: Microstructure, Degradation, and In Vitro Cell Behavior2296-418510.3389/fbioe.2021.783821https://doaj.org/article/838edbfc8e164773823ab0a066100bc42021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fbioe.2021.783821/fullhttps://doaj.org/toc/2296-4185A too slow degradation of iron (Fe) limits its orthopedic application. In this study, calcium chloride (CaCl2) was incorporated into a Fe-based biocomposite fabricated by laser additive manufacturing, with an aim to accelerate the degradation. It was found that CaCl2 with strong water absorptivity improved the hydrophilicity of the Fe matrix and thereby promoted the invasion of corrosive solution. On the other hand, CaCl2 could rapidly dissolve once contacting the solution and release massive chloride ion. Interestingly, the local high concentration of chloride ion effectively destroyed the corrosion product layer due to its strong erosion ability. As a result, the corrosion product layer covered on the Fe/CaCl2 matrix exhibited an extremely porous structure, thus exhibiting a significantly reduced corrosion resistance. Besides, in vivo cell testing proved that the Fe/CaCl2 biocomposite also showed favorable cytocompatibility.Youwen YangGuoqing CaiMingli YangDongsheng WangShuping PengShuping PengZhigang LiuCijun ShuaiCijun ShuaiFrontiers Media S.A.articlelaser additive manufacturingiron bone implantcalcium chloridedegradation propertiescell behaviorBiotechnologyTP248.13-248.65ENFrontiers in Bioengineering and Biotechnology, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	laser additive manufacturing iron bone implant calcium chloride degradation properties cell behavior Biotechnology TP248.13-248.65
spellingShingle	laser additive manufacturing iron bone implant calcium chloride degradation properties cell behavior Biotechnology TP248.13-248.65 Youwen Yang Guoqing Cai Mingli Yang Dongsheng Wang Shuping Peng Shuping Peng Zhigang Liu Cijun Shuai Cijun Shuai Laser Additively Manufactured Iron-Based Biocomposite: Microstructure, Degradation, and In Vitro Cell Behavior
description	A too slow degradation of iron (Fe) limits its orthopedic application. In this study, calcium chloride (CaCl2) was incorporated into a Fe-based biocomposite fabricated by laser additive manufacturing, with an aim to accelerate the degradation. It was found that CaCl2 with strong water absorptivity improved the hydrophilicity of the Fe matrix and thereby promoted the invasion of corrosive solution. On the other hand, CaCl2 could rapidly dissolve once contacting the solution and release massive chloride ion. Interestingly, the local high concentration of chloride ion effectively destroyed the corrosion product layer due to its strong erosion ability. As a result, the corrosion product layer covered on the Fe/CaCl2 matrix exhibited an extremely porous structure, thus exhibiting a significantly reduced corrosion resistance. Besides, in vivo cell testing proved that the Fe/CaCl2 biocomposite also showed favorable cytocompatibility.
format	article
author	Youwen Yang Guoqing Cai Mingli Yang Dongsheng Wang Shuping Peng Shuping Peng Zhigang Liu Cijun Shuai Cijun Shuai
author_facet	Youwen Yang Guoqing Cai Mingli Yang Dongsheng Wang Shuping Peng Shuping Peng Zhigang Liu Cijun Shuai Cijun Shuai
author_sort	Youwen Yang
title	Laser Additively Manufactured Iron-Based Biocomposite: Microstructure, Degradation, and In Vitro Cell Behavior
title_short	Laser Additively Manufactured Iron-Based Biocomposite: Microstructure, Degradation, and In Vitro Cell Behavior
title_full	Laser Additively Manufactured Iron-Based Biocomposite: Microstructure, Degradation, and In Vitro Cell Behavior
title_fullStr	Laser Additively Manufactured Iron-Based Biocomposite: Microstructure, Degradation, and In Vitro Cell Behavior
title_full_unstemmed	Laser Additively Manufactured Iron-Based Biocomposite: Microstructure, Degradation, and In Vitro Cell Behavior
title_sort	laser additively manufactured iron-based biocomposite: microstructure, degradation, and in vitro cell behavior
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/838edbfc8e164773823ab0a066100bc4
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Laser Additively Manufactured Iron-Based Biocomposite: Microstructure, Degradation, and In Vitro Cell Behavior

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