MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY

This work is aimed at the determination of the level of molecules of intercellular adhesion of sICAM-1 and sVCAM-1 in the persons exposed to mercury. All the examined persons (88 males of 31-62) were divided into three groups: the persons with the diagnosis of chronic mercury intoxication in the pos...

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Autores principales:	O. V. Popkova, I. V. Kudaeva, L. B. Masnavieva
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2013
Materias:	sicam-1 svcam-1 chronic exposure to mercury chronic mercury intoxication endothelial dysfunction inflammation molecules of intercellular adhesion Science Q
Acceso en línea:	https://doaj.org/article/8391d77e84494a90943de3441b00b9b5
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id	oai:doaj.org-article:8391d77e84494a90943de3441b00b9b5
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spelling	oai:doaj.org-article:8391d77e84494a90943de3441b00b9b52021-11-23T06:14:28ZMOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY2541-94202587-9596https://doaj.org/article/8391d77e84494a90943de3441b00b9b52013-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1560https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596This work is aimed at the determination of the level of molecules of intercellular adhesion of sICAM-1 and sVCAM-1 in the persons exposed to mercury. All the examined persons (88 males of 31-62) were divided into three groups: the persons with the diagnosis of chronic mercury intoxication in the postponed postcontact period (1st group); the persons with the first revealed diagnosis (2nd group); the persons without professional disease working under harmful conditions for more than 5 years. Determination of the molecules was conducted using immune-enzymatic analysis method. The levels of sICAM-1 didn't differ in the 1st and 2nd groups and came to 466,2 and 430,2 ng/ml respectively, the level of sICAM-1 in the 3rd group was 219,1 ng/ml. The sVCAM-1 concentration was 337,8,126,8 and 327,4 ng/ml in the 1st, 2nd and 3rd group respectively. Increasing sVCAM-1 levels in the workers with long-term work period indicate the activation of endothelial vessel. Increased levels of sICAM-1 in patients with cardiovascular disease are related to the pathogenesis of cardiovascular disease or chronic mercury intoxication.O. V. PopkovaI. V. KudaevaL. B. MasnavievaScientific Сentre for Family Health and Human Reproduction Problemsarticlesicam-1svcam-1chronic exposure to mercurychronic mercury intoxicationendothelial dysfunctioninflammationmolecules of intercellular adhesionsicam-1svcam-1ScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3(1), Pp 30-33 (2013)
institution	DOAJ
collection	DOAJ
language	RU
topic	sicam-1 svcam-1 chronic exposure to mercury chronic mercury intoxication endothelial dysfunction inflammation molecules of intercellular adhesion sicam-1 svcam-1 Science Q
spellingShingle	sicam-1 svcam-1 chronic exposure to mercury chronic mercury intoxication endothelial dysfunction inflammation molecules of intercellular adhesion sicam-1 svcam-1 Science Q O. V. Popkova I. V. Kudaeva L. B. Masnavieva MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY
description	This work is aimed at the determination of the level of molecules of intercellular adhesion of sICAM-1 and sVCAM-1 in the persons exposed to mercury. All the examined persons (88 males of 31-62) were divided into three groups: the persons with the diagnosis of chronic mercury intoxication in the postponed postcontact period (1st group); the persons with the first revealed diagnosis (2nd group); the persons without professional disease working under harmful conditions for more than 5 years. Determination of the molecules was conducted using immune-enzymatic analysis method. The levels of sICAM-1 didn't differ in the 1st and 2nd groups and came to 466,2 and 430,2 ng/ml respectively, the level of sICAM-1 in the 3rd group was 219,1 ng/ml. The sVCAM-1 concentration was 337,8,126,8 and 327,4 ng/ml in the 1st, 2nd and 3rd group respectively. Increasing sVCAM-1 levels in the workers with long-term work period indicate the activation of endothelial vessel. Increased levels of sICAM-1 in patients with cardiovascular disease are related to the pathogenesis of cardiovascular disease or chronic mercury intoxication.
format	article
author	O. V. Popkova I. V. Kudaeva L. B. Masnavieva
author_facet	O. V. Popkova I. V. Kudaeva L. B. Masnavieva
author_sort	O. V. Popkova
title	MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY
title_short	MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY
title_full	MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY
title_fullStr	MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY
title_full_unstemmed	MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY
title_sort	molecules of intercellular adhesion in blood sera of persons exposed to mercury
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2013
url	https://doaj.org/article/8391d77e84494a90943de3441b00b9b5
work_keys_str_mv	AT ovpopkova moleculesofintercellularadhesioninbloodseraofpersonsexposedtomercury AT ivkudaeva moleculesofintercellularadhesioninbloodseraofpersonsexposedtomercury AT lbmasnavieva moleculesofintercellularadhesioninbloodseraofpersonsexposedtomercury
_version_	1718417143299571712

MOLECULES OF INTERCELLULAR ADHESION IN BLOOD SERA OF PERSONS EXPOSED TO MERCURY

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