Functional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells

Functional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells

Injury of corpus cavernosa results in erectile dysfunction, and repair leading to restoration of function is difficult. Here the authors construct 3D printed hydrogel constructs seeded with HIF-1α-expressing muscle derived stem cells to restore corpus function in a rabbit model.

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Autores principales: Geng An, Feixiang Guo, Xuemin Liu, Zhifang Wang, Ye Zhu, Yong Fan, Chengkai Xuan, Yan Li, Hongkai Wu, Xuetao Shi, Chuanbin Mao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8396d45b6c5b49b8999636788a85c4b8
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spelling oai:doaj.org-article:8396d45b6c5b49b8999636788a85c4b82021-12-02T15:56:39ZFunctional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells10.1038/s41467-020-16192-x2041-1723https://doaj.org/article/8396d45b6c5b49b8999636788a85c4b82020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16192-xhttps://doaj.org/toc/2041-1723Injury of corpus cavernosa results in erectile dysfunction, and repair leading to restoration of function is difficult. Here the authors construct 3D printed hydrogel constructs seeded with HIF-1α-expressing muscle derived stem cells to restore corpus function in a rabbit model.Geng AnFeixiang GuoXuemin LiuZhifang WangYe ZhuYong FanChengkai XuanYan LiHongkai WuXuetao ShiChuanbin MaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Geng An
Feixiang Guo
Xuemin Liu
Zhifang Wang
Ye Zhu
Yong Fan
Chengkai Xuan
Yan Li
Hongkai Wu
Xuetao Shi
Chuanbin Mao
Functional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells
description Injury of corpus cavernosa results in erectile dysfunction, and repair leading to restoration of function is difficult. Here the authors construct 3D printed hydrogel constructs seeded with HIF-1α-expressing muscle derived stem cells to restore corpus function in a rabbit model.
format article
author Geng An
Feixiang Guo
Xuemin Liu
Zhifang Wang
Ye Zhu
Yong Fan
Chengkai Xuan
Yan Li
Hongkai Wu
Xuetao Shi
Chuanbin Mao
author_facet Geng An
Feixiang Guo
Xuemin Liu
Zhifang Wang
Ye Zhu
Yong Fan
Chengkai Xuan
Yan Li
Hongkai Wu
Xuetao Shi
Chuanbin Mao
author_sort Geng An
title Functional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells
title_short Functional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells
title_full Functional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells
title_fullStr Functional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells
title_full_unstemmed Functional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells
title_sort functional reconstruction of injured corpus cavernosa using 3d-printed hydrogel scaffolds seeded with hif-1α-expressing stem cells
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/8396d45b6c5b49b8999636788a85c4b8
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