Receptor-induced thiolate couples Env activation to retrovirus fusion and infection.

According to current models of retrovirus infection, receptor binding to the surface subunit (SU) of the envelope glycoprotein (Env) triggers a conformational change in the transmembrane subunit (TM) that mediates virus fusion to cell membranes. To understand how this occurs, we investigated the rol...

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Bibliographic Details
Main Authors: Jason G Smith, James M Cunningham
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2007
Subjects:
Online Access:https://doaj.org/article/83a121dcb80b48e1a8ee66bebac040c0
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