Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology

Serum liver enzymes are used as markers of liver disease, their concentration influenced in part by genetic factors. Here the authors meta-analyse genome-wide association studies on the UK Biobank and BioBank Japan to evaluate the association of three liver enzymes with liver and other metabolic dis...

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Autores principales:	Vincent L. Chen, Xiaomeng Du, Yanhua Chen, Annapurna Kuppa, Samuel K. Handelman, Rishel B. Vohnoutka, Patricia A. Peyser, Nicholette D. Palmer, Lawrence F. Bielak, Brian Halligan, Elizabeth K. Speliotes
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/83b170469b994a178b736003c46c40b3
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spelling	oai:doaj.org-article:83b170469b994a178b736003c46c40b32021-12-02T14:06:28ZGenome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology10.1038/s41467-020-20870-12041-1723https://doaj.org/article/83b170469b994a178b736003c46c40b32021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20870-1https://doaj.org/toc/2041-1723Serum liver enzymes are used as markers of liver disease, their concentration influenced in part by genetic factors. Here the authors meta-analyse genome-wide association studies on the UK Biobank and BioBank Japan to evaluate the association of three liver enzymes with liver and other metabolic diseases.Vincent L. ChenXiaomeng DuYanhua ChenAnnapurna KuppaSamuel K. HandelmanRishel B. VohnoutkaPatricia A. PeyserNicholette D. PalmerLawrence F. BielakBrian HalliganElizabeth K. SpeliotesNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Vincent L. Chen Xiaomeng Du Yanhua Chen Annapurna Kuppa Samuel K. Handelman Rishel B. Vohnoutka Patricia A. Peyser Nicholette D. Palmer Lawrence F. Bielak Brian Halligan Elizabeth K. Speliotes Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology
description	Serum liver enzymes are used as markers of liver disease, their concentration influenced in part by genetic factors. Here the authors meta-analyse genome-wide association studies on the UK Biobank and BioBank Japan to evaluate the association of three liver enzymes with liver and other metabolic diseases.
format	article
author	Vincent L. Chen Xiaomeng Du Yanhua Chen Annapurna Kuppa Samuel K. Handelman Rishel B. Vohnoutka Patricia A. Peyser Nicholette D. Palmer Lawrence F. Bielak Brian Halligan Elizabeth K. Speliotes
author_facet	Vincent L. Chen Xiaomeng Du Yanhua Chen Annapurna Kuppa Samuel K. Handelman Rishel B. Vohnoutka Patricia A. Peyser Nicholette D. Palmer Lawrence F. Bielak Brian Halligan Elizabeth K. Speliotes
author_sort	Vincent L. Chen
title	Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology
title_short	Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology
title_full	Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology
title_fullStr	Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology
title_full_unstemmed	Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology
title_sort	genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/83b170469b994a178b736003c46c40b3
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Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology

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