Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase
O-linked β-N-acetyl glucosamine (O-GlcNAc) is an important protein modification that is hydrolyzed by O-GlcNAcase (OGA). Here the authors give insights into OGA substrate recognition by presenting four human OGA structures complexed with glycopeptide substrates containing a single O-GlcNAc modificat...
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Autores principales: | Baobin Li, Hao Li, Chia-Wei Hu, Jiaoyang Jiang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/83dd0423da5d4c818b6d5f0359d95d24 |
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