Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension

How paraxial mesoderm formation and differentiation is regulated is unclear. Here, the authors identify accessible chromatin and gene expression signatures that define different stages of paraxial mesoderm development in the chick and identify CREs important for vertebrate anterior–posterior axis fo...

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Autores principales:	Gi Fay Mok, Leighton Folkes, Shannon A. Weldon, Eirini Maniou, Victor Martinez-Heredia, Alice M. Godden, Ruth M. Williams, Tatjana Sauka-Spengler, Grant N. Wheeler, Simon Moxon, Andrea E. Münsterberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/83e65e791fea4260aa9246e9733957f6
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spelling	oai:doaj.org-article:83e65e791fea4260aa9246e9733957f62021-12-02T12:11:51ZCharacterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension10.1038/s41467-021-21426-72041-1723https://doaj.org/article/83e65e791fea4260aa9246e9733957f62021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21426-7https://doaj.org/toc/2041-1723How paraxial mesoderm formation and differentiation is regulated is unclear. Here, the authors identify accessible chromatin and gene expression signatures that define different stages of paraxial mesoderm development in the chick and identify CREs important for vertebrate anterior–posterior axis formation.Gi Fay MokLeighton FolkesShannon A. WeldonEirini ManiouVictor Martinez-HerediaAlice M. GoddenRuth M. WilliamsTatjana Sauka-SpenglerGrant N. WheelerSimon MoxonAndrea E. MünsterbergNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gi Fay Mok Leighton Folkes Shannon A. Weldon Eirini Maniou Victor Martinez-Heredia Alice M. Godden Ruth M. Williams Tatjana Sauka-Spengler Grant N. Wheeler Simon Moxon Andrea E. Münsterberg Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension
description	How paraxial mesoderm formation and differentiation is regulated is unclear. Here, the authors identify accessible chromatin and gene expression signatures that define different stages of paraxial mesoderm development in the chick and identify CREs important for vertebrate anterior–posterior axis formation.
format	article
author	Gi Fay Mok Leighton Folkes Shannon A. Weldon Eirini Maniou Victor Martinez-Heredia Alice M. Godden Ruth M. Williams Tatjana Sauka-Spengler Grant N. Wheeler Simon Moxon Andrea E. Münsterberg
author_facet	Gi Fay Mok Leighton Folkes Shannon A. Weldon Eirini Maniou Victor Martinez-Heredia Alice M. Godden Ruth M. Williams Tatjana Sauka-Spengler Grant N. Wheeler Simon Moxon Andrea E. Münsterberg
author_sort	Gi Fay Mok
title	Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension
title_short	Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension
title_full	Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension
title_fullStr	Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension
title_full_unstemmed	Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension
title_sort	characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/83e65e791fea4260aa9246e9733957f6
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Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension

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