Virtual screening as a tool to discover new β-haematin inhibitors with activity against malaria parasites

Abstract Malaria remains a major public health problem. With the loss of antimalarials to resistance, the malaria burden will likely continue for decades. New antimalarial scaffolds are crucial to avoid cross-resistance. Here, we present the first structure based virtual screening using the β-haemat...

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Autores principales: Ana Carolina C. de Sousa, Jill M. Combrinck, Keletso Maepa, Timothy J. Egan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/83eb3cf1f04445ff916522570afe1d21
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