Routine antibiotics may not be needed to treat uncomplicated right diverticulitis: A retrospective cohort study.

We aimed to investigate whether antibiotic administration is necessary for patients with uncomplicated right colonic diverticulitis. Data from patients diagnosed with uncomplicated right colonic diverticulitis, who received inpatient treatment at a single center between January 2019 and January 2021...

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Autores principales:	Kil-Yong Lee, Jaeim Lee, Youn Young Park, Seong Taek Oh
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/83ebe3c034674ee3a02659af1e5cc16a
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spelling	oai:doaj.org-article:83ebe3c034674ee3a02659af1e5cc16a2021-12-02T20:08:53ZRoutine antibiotics may not be needed to treat uncomplicated right diverticulitis: A retrospective cohort study.1932-620310.1371/journal.pone.0255384https://doaj.org/article/83ebe3c034674ee3a02659af1e5cc16a2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0255384https://doaj.org/toc/1932-6203We aimed to investigate whether antibiotic administration is necessary for patients with uncomplicated right colonic diverticulitis. Data from patients diagnosed with uncomplicated right colonic diverticulitis, who received inpatient treatment at a single center between January 2019 and January 2021, were retrospectively examined. The patients were divided into two groups according to whether antibiotics were administered. The patients were matched between groups using propensity score matching in a 1:1 ratio using logistic regression with the nearest-neighbor method. The primary study outcome was the length of hospital stay, and the secondary outcomes were time to the introduction of sips of water and a soft diet. The study included 138 patients who received antibiotics and 59 who did not. After propensity score matching, 55 patients were assigned to each treatment group. There was no significant difference between the two groups in terms of age (p = 0.772), sex (p>0.999), body mass index (p = 0.121), prehospital symptom duration (p = 0.727), initial body temperature (p = 0.661), white blood cell count (p = 0.688), or C-reactive protein level (p = 0.337). There was also no statistically significant difference in the length of hospital stay between the no antibiotic and antibiotic groups (3.1±0.7 days vs. 3.0±1.0 days, p = 0.584). Additionally, no significant difference was observed between the no antibiotic and antibiotic groups with respect to time to sips of water (2.1±0.7 days vs. 1.8±0.9 days, p = 0.100) and time to the introduction of a soft diet (2.4±0.8 days vs. 2.1±0.9 days, p = 0.125). The findings suggest that routine antibiotics may be not required for treating patients with uncomplicated right colonic diverticulitis.Kil-Yong LeeJaeim LeeYoun Young ParkSeong Taek OhPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 7, p e0255384 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Kil-Yong Lee Jaeim Lee Youn Young Park Seong Taek Oh Routine antibiotics may not be needed to treat uncomplicated right diverticulitis: A retrospective cohort study.
description	We aimed to investigate whether antibiotic administration is necessary for patients with uncomplicated right colonic diverticulitis. Data from patients diagnosed with uncomplicated right colonic diverticulitis, who received inpatient treatment at a single center between January 2019 and January 2021, were retrospectively examined. The patients were divided into two groups according to whether antibiotics were administered. The patients were matched between groups using propensity score matching in a 1:1 ratio using logistic regression with the nearest-neighbor method. The primary study outcome was the length of hospital stay, and the secondary outcomes were time to the introduction of sips of water and a soft diet. The study included 138 patients who received antibiotics and 59 who did not. After propensity score matching, 55 patients were assigned to each treatment group. There was no significant difference between the two groups in terms of age (p = 0.772), sex (p>0.999), body mass index (p = 0.121), prehospital symptom duration (p = 0.727), initial body temperature (p = 0.661), white blood cell count (p = 0.688), or C-reactive protein level (p = 0.337). There was also no statistically significant difference in the length of hospital stay between the no antibiotic and antibiotic groups (3.1±0.7 days vs. 3.0±1.0 days, p = 0.584). Additionally, no significant difference was observed between the no antibiotic and antibiotic groups with respect to time to sips of water (2.1±0.7 days vs. 1.8±0.9 days, p = 0.100) and time to the introduction of a soft diet (2.4±0.8 days vs. 2.1±0.9 days, p = 0.125). The findings suggest that routine antibiotics may be not required for treating patients with uncomplicated right colonic diverticulitis.
format	article
author	Kil-Yong Lee Jaeim Lee Youn Young Park Seong Taek Oh
author_facet	Kil-Yong Lee Jaeim Lee Youn Young Park Seong Taek Oh
author_sort	Kil-Yong Lee
title	Routine antibiotics may not be needed to treat uncomplicated right diverticulitis: A retrospective cohort study.
title_short	Routine antibiotics may not be needed to treat uncomplicated right diverticulitis: A retrospective cohort study.
title_full	Routine antibiotics may not be needed to treat uncomplicated right diverticulitis: A retrospective cohort study.
title_fullStr	Routine antibiotics may not be needed to treat uncomplicated right diverticulitis: A retrospective cohort study.
title_full_unstemmed	Routine antibiotics may not be needed to treat uncomplicated right diverticulitis: A retrospective cohort study.
title_sort	routine antibiotics may not be needed to treat uncomplicated right diverticulitis: a retrospective cohort study.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/83ebe3c034674ee3a02659af1e5cc16a
work_keys_str_mv	AT kilyonglee routineantibioticsmaynotbeneededtotreatuncomplicatedrightdiverticulitisaretrospectivecohortstudy AT jaeimlee routineantibioticsmaynotbeneededtotreatuncomplicatedrightdiverticulitisaretrospectivecohortstudy AT younyoungpark routineantibioticsmaynotbeneededtotreatuncomplicatedrightdiverticulitisaretrospectivecohortstudy AT seongtaekoh routineantibioticsmaynotbeneededtotreatuncomplicatedrightdiverticulitisaretrospectivecohortstudy
_version_	1718375134468767744

Routine antibiotics may not be needed to treat uncomplicated right diverticulitis: A retrospective cohort study.

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