Sex-Specific Causal Relations between Steroid Hormones and Obesity—A Mendelian Randomization Study

Sex-Specific Causal Relations between Steroid Hormones and Obesity—A Mendelian Randomization Study

Steroid hormones act as important regulators of physiological processes including gene expression. They provide possible mechanistic explanations of observed sex-dimorphisms in obesity and coronary artery disease (CAD). Here, we aim to unravel causal relationships between steroid hormones, obesity,...

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Main Authors: Janne Pott, Katrin Horn, Robert Zeidler, Holger Kirsten, Peter Ahnert, Jürgen Kratzsch, Markus Loeffler, Berend Isermann, Uta Ceglarek, Markus Scholz
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
steroid hormones
sexual dimorphism
genome-wide association analysis
Mendelian randomization
coronary artery disease
obesity
Microbiology
QR1-502
Online Access:https://doaj.org/article/83f02438365d44a29c2fbdfab5d5bbe4
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https://doaj.org/article/83f02438365d44a29c2fbdfab5d5bbe4

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