TALEN based HPV-E7 editing triggers necrotic cell death in cervical cancer cells

TALEN based HPV-E7 editing triggers necrotic cell death in cervical cancer cells

Abstract Human Papillomavirus E7 and E6 oncoproteins have been considered as suitable candidate anti-viral targets since they cause malignant conversion in cervical cancers. Transcription Activator-Like Effector Nucleases (TALENs) are recent editing tools to knockout genes by inducing double strande...

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Autores principales: Sumitra Shankar, Deepti Prasad, Rahul Sanawar, Ani V. Das, M. Radhakrishna Pillai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/83f53160399a4bffbbcca8110f2ae7a9
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