Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice

Components of the seminal fluid are required for specific gene expression and immune changes in the uterus following mating, but the role that sperm play in this process has remained unclear. Here, John Schjenken et al. compare female mice mated to intact and vasectomized males and show that sperm a...

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Autores principales:	John E. Schjenken, David J. Sharkey, Ella S. Green, Hon Yeung Chan, Ricky A. Matias, Lachlan M. Moldenhauer, Sarah A. Robertson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/84058944357844abadb2a9c35f93e128
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spelling	oai:doaj.org-article:84058944357844abadb2a9c35f93e1282021-12-02T17:15:22ZSperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice10.1038/s42003-021-02038-92399-3642https://doaj.org/article/84058944357844abadb2a9c35f93e1282021-05-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02038-9https://doaj.org/toc/2399-3642Components of the seminal fluid are required for specific gene expression and immune changes in the uterus following mating, but the role that sperm play in this process has remained unclear. Here, John Schjenken et al. compare female mice mated to intact and vasectomized males and show that sperm are required for the full post-mating response, indicating a broader role for sperm in reproduction beyond fertilization.John E. SchjenkenDavid J. SharkeyElla S. GreenHon Yeung ChanRicky A. MatiasLachlan M. MoldenhauerSarah A. RobertsonNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 John E. Schjenken David J. Sharkey Ella S. Green Hon Yeung Chan Ricky A. Matias Lachlan M. Moldenhauer Sarah A. Robertson Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice
description	Components of the seminal fluid are required for specific gene expression and immune changes in the uterus following mating, but the role that sperm play in this process has remained unclear. Here, John Schjenken et al. compare female mice mated to intact and vasectomized males and show that sperm are required for the full post-mating response, indicating a broader role for sperm in reproduction beyond fertilization.
format	article
author	John E. Schjenken David J. Sharkey Ella S. Green Hon Yeung Chan Ricky A. Matias Lachlan M. Moldenhauer Sarah A. Robertson
author_facet	John E. Schjenken David J. Sharkey Ella S. Green Hon Yeung Chan Ricky A. Matias Lachlan M. Moldenhauer Sarah A. Robertson
author_sort	John E. Schjenken
title	Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice
title_short	Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice
title_full	Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice
title_fullStr	Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice
title_full_unstemmed	Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice
title_sort	sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/84058944357844abadb2a9c35f93e128
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Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice

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