Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination

Demyelination results in impairments in oligodendrocyte progenitor cell recruitment. Here the authors identify sulfatase 1/2 as a potential modulator of myelination by modulating the microenvironment around oligodendrocyte progenitor cells.

Guardado en:
Detalles Bibliográficos
Autores principales: Darpan Saraswat, Hani J. Shayya, Jessie J. Polanco, Ajai Tripathi, R. Ross Welliver, Suyog U. Pol, Richard A. Seidman, Jacqueline E. Broome, Melanie A. O’Bara, Toin H. van Kuppervelt, Joanna J. Phillips, Ranjan Dutta, Fraser J. Sim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Q
Acceso en línea:https://doaj.org/article/8405f74419104281af9993328f364b19
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:8405f74419104281af9993328f364b19
record_format dspace
spelling oai:doaj.org-article:8405f74419104281af9993328f364b192021-12-02T13:24:12ZOvercoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination10.1038/s41467-021-22263-42041-1723https://doaj.org/article/8405f74419104281af9993328f364b192021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22263-4https://doaj.org/toc/2041-1723Demyelination results in impairments in oligodendrocyte progenitor cell recruitment. Here the authors identify sulfatase 1/2 as a potential modulator of myelination by modulating the microenvironment around oligodendrocyte progenitor cells.Darpan SaraswatHani J. ShayyaJessie J. PolancoAjai TripathiR. Ross WelliverSuyog U. PolRichard A. SeidmanJacqueline E. BroomeMelanie A. O’BaraToin H. van KupperveltJoanna J. PhillipsRanjan DuttaFraser J. SimNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Darpan Saraswat
Hani J. Shayya
Jessie J. Polanco
Ajai Tripathi
R. Ross Welliver
Suyog U. Pol
Richard A. Seidman
Jacqueline E. Broome
Melanie A. O’Bara
Toin H. van Kuppervelt
Joanna J. Phillips
Ranjan Dutta
Fraser J. Sim
Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination
description Demyelination results in impairments in oligodendrocyte progenitor cell recruitment. Here the authors identify sulfatase 1/2 as a potential modulator of myelination by modulating the microenvironment around oligodendrocyte progenitor cells.
format article
author Darpan Saraswat
Hani J. Shayya
Jessie J. Polanco
Ajai Tripathi
R. Ross Welliver
Suyog U. Pol
Richard A. Seidman
Jacqueline E. Broome
Melanie A. O’Bara
Toin H. van Kuppervelt
Joanna J. Phillips
Ranjan Dutta
Fraser J. Sim
author_facet Darpan Saraswat
Hani J. Shayya
Jessie J. Polanco
Ajai Tripathi
R. Ross Welliver
Suyog U. Pol
Richard A. Seidman
Jacqueline E. Broome
Melanie A. O’Bara
Toin H. van Kuppervelt
Joanna J. Phillips
Ranjan Dutta
Fraser J. Sim
author_sort Darpan Saraswat
title Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination
title_short Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination
title_full Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination
title_fullStr Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination
title_full_unstemmed Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination
title_sort overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8405f74419104281af9993328f364b19
work_keys_str_mv AT darpansaraswat overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
AT hanijshayya overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
AT jessiejpolanco overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
AT ajaitripathi overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
AT rrosswelliver overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
AT suyogupol overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
AT richardaseidman overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
AT jacquelineebroome overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
AT melanieaobara overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
AT toinhvankuppervelt overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
AT joannajphillips overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
AT ranjandutta overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
AT fraserjsim overcomingtheinhibitorymicroenvironmentsurroundingoligodendrocyteprogenitorcellsfollowingexperimentaldemyelination
_version_ 1718393105309237248